Loxoprofen

Loxoprofen
  • CAS No.:68767-14-6
Other grades of this product :
Loxoprofen Basic information
Product Name:Loxoprofen
Synonyms:IOXOPROFEN;2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid;KOLOXO;LOXOPROFEN;2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID;A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID;α-methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid;2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
CAS:68767-14-6
MF:C15H18O3
MW:246.31
EINECS:1806241-263-5
Product Categories:LOXONIN;Active Pharmaceutical Ingredients
Mol File:68767-14-6.mol
Loxoprofen Chemical Properties
Melting point 108.5-111°
Boiling point bp0.3 190-195°
density 1.182±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.39±0.10(Predicted)
form solid
color White to Off-White
Merck 14,5589
CAS DataBase Reference68767-14-6(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
MSDS Information
Loxoprofen Usage And Synthesis
Usesantiinflammatory, analgesic
UsesLoxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
DefinitionChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted to its active trans-alcohol metabolite following ora administration.

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