Vindesine sulfate

CAS No.：59917-39-4

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Vindesine sulfate Basic information

Product Name:	Vindesine sulfate
Synonyms:	Desacetylvinblastine amide sulfate salt;Fildesi;LY-099094;VINCRISITINESULFATE;Vincaleukoblastine, 3-(aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)-, sulfate (1:1) (salt);VINDESINE SULFATE SALT;Methyl (1S,13S,15S,17S)-13-[(1R,9R,10S,11R,12R,19R)-10-carbaMoyl-12-ethyl-10,11-dihydroxy-5-Methoxy-8-Methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.;Elsedine
CAS:	59917-39-4
MF:	C43H57N5O11S
MW:	852
EINECS:	261-984-7
Product Categories:	Anti-cancer & immunity;Intermediates & Fine Chemicals;Pharmaceuticals;APIs
Mol File:	59917-39-4.mol

Vindesine sulfate Chemical Properties

Melting point	>2500C
storage temp.	2-8°C
solubility	deionized water: ≥50mg/mL
form	powder
color	off-white to light yellow
Stability:	Hygroscopic

Safety Information

Hazard Codes	Xn
Risk Statements	40
Safety Statements	26-36
RIDADR	1544
WGK Germany	3
RTECS	YY8090000
HazardClass	6.1(a)
PackingGroup	II
Toxicity	LD50 in mice, rats (mg/kg): 6.3 ± 0.6, 2.0 ± 0.2 i.v. (Todd); in mice: 8.8 ± 2.5 i.p. (Owellen, Biochem. Pharmacol.)

MSDS Information

Vindesine sulfate Usage And Synthesis

Chemical Properties	Amorphous Solid
Uses	anticancer
Uses	Synthetic derivative of the dimeric Catharanthus alkaloid vinblastine. Antineoplastic
Uses	Vindesine Sulfate Salt is a synthetic derivative of the dimeric Catharanthus alkaloid vinblastine. Antineoplastic.
Brand name	Eldisine (Lilly).

Vindesine sulfate Preparation Products And Raw materials

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