Flusilazole

Flusilazole
  • CAS No.:85509-19-9
Other grades of this product :
Flusilazole Basic information
Product Name:Flusilazole
Synonyms:(bis(4-fluorophenyl))(methyl)(1h-1,2,4-triazol-1-ylmethyl)-silan;4-triazole,1-((bis(4-fluorophenyl)methylsilyl)methyl)-1h-2;dpx-h6573;1H-1,2,4-Triazole, 1-bis(4-fluorophenyl)methylsilylmethyl-;flusilazole (ansi,bsi,iso);flusilazole (ISO) bis(4-fluorophenyl)(methyl)(1H-1,2,4-triazol-1-ylmethyl)silane;Benocarp;Flusilazole 100mg [85509-19-9]
CAS:85509-19-9
MF:C16H15F2N3Si
MW:315.4
EINECS:
Product Categories:ConazolesAlphabetic;Alpha sort;ConazolesPesticides&Metabolites;E-GAlphabetic;F;FA - FL;Fungicide;Special Silanes;Fungicides;Pesticides
Mol File:85509-19-9.mol
Flusilazole Chemical Properties
Melting point 55°
Boiling point 393 °C [760mmHg]
density 1.17
vapor pressure 3.9 x l0-8 Pa (25 °C)
refractive index 1.563
Fp 192°C
storage temp. 0-6°C
form neat
pka2.5 at 25℃
Water Solubility 900 mg l-1 (pH 1.1), 50 mg l-1 (pH 5.7), 45 mg l-1 (pH 7.8) at 25 °C
Merck 13,4232
BRN 5824097
CAS DataBase Reference85509-19-9(CAS DataBase Reference)
EPA Substance Registry SystemFlusilazole (85509-19-9)
Safety Information
Hazard Codes T;N,N,T
Risk Statements 61-22-40-51/53
Safety Statements 53-45-61
RIDADR UN 2588
WGK Germany 3
RTECS XZ4105000
ToxicityLD50 in male, female rats (mg/kg): 1110, 674 orally; in rabbits >2000 dermally (Fort, Moberg)
MSDS Information
Flusilazole Usage And Synthesis
Chemical PropertiesBrown-red viscous liquid
UsesFlusilazole is a silicon-containing triazole fungicide. Flusilazole is used to control fungal infections on a variety of fruit and vegetable crops
UsesAgricultural fungicide.
UsesFlusilazole is a broad spectrum fungicide used to control fungal disease caused by pathogens of the Ascomycetes, Basidiomycetes and Deuteromycetes families. Flusilazole exhibits curative and preventative activities and is recommended for use in agriculture, horticulture and viticulture. Diseases controlled include eyespot, mildew, and rusts of cereals, cercospora and rust of sugar beets, leaf spots of oilseed rape, scab and mildew of pome and stone fruits, mildew and black rot of grapes and Sigatoka disease of bananas.
Metabolic pathwayFlusilazole is stable to aqueous hydrolytic and photolytic degradation. Although flusilazole is relatively stable in soil and is detected in plant and animal samples, numerous degradation products have been reported. The primary metabolic pathway involves the cleavage of the methylenesilicon or/and methylene-triazole linkage. Another primary pathway involves aryl hydroxylation followed by conjugation. The primary metabolic/degradation pathways of flusilazole in soil, plant and animals are presented in Scheme 1.
DegradationAqueous hydrolysis and photolysis are not sigruficant degradation pathways for flusilazole (1). Flusilazole was stable (<5% decomposition) in sterile buffers at pH 5, 7 and 9 (25 °C) for 34 days (Cadwgan, 1983). No significant degradation was observed when fusilazole was irradiated with simulated sunlight for 30 days at 300-450 nm in sterile buffer solution at pH 7 (Carter, 1986).
Flusilazole Preparation Products And Raw materials
Raw materialsn-Butyllithium-->Fluorobenzene-->Silicon tetrahydride-->METHYLSILANE-->1,2,4-Triazolylsodium

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