| (R)-(+)-1-Benzyl-3-pyrrolidinol Basic information |
| Product Name: | (R)-(+)-1-Benzyl-3-pyrrolidinol |
| Synonyms: | (R)-3-HYDROXYPYRROLIDINE, N-BENZYL;(r)-3-hydroxy-1-benyzl-pyrrolidine;(R)-3-HYDROXY-1-BENZYL-PYRROLIDINE;(R)-1-BENZYL-PYRROLIDIN-3-OL;(R)-1-N-BENZYL-3-HYDROXYPYRROLIDINE;(R)-(+)-1-BENZYL-3-PYRROLIDINOL;(R)-1-BENZYL-3-PYRROLIDINOL;(R)-1-BENZYL-3-HYDROXYPYRROLIDINE |
| CAS: | 101930-07-8 |
| MF: | C11H15NO |
| MW: | 177.24 |
| EINECS: | |
| Product Categories: | Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Chiral Building Blocks;Heterocyclic Building Blocks;Pyrrolidines;Pyrrole&Pyrrolidine&Pyrroline;Benzenes |
| Mol File: | 101930-07-8.mol |
| (R)-(+)-1-Benzyl-3-pyrrolidinol Chemical Properties |
| alpha | 3.7 º (c=5, MeOH) |
| Boiling point | 116 °C0.9 mm Hg(lit.) |
| density | 1.07 g/mL at 25 °C(lit.) |
| refractive index | n |
| Fp | >230 °F |
| storage temp. | 2-8°C |
| pka | 14.82±0.20(Predicted) |
| form | clear liquid to slightly cloudy liquid |
| color | Light yellow to Yellow to Orange |
| Specific Gravity | 1.07 |
| optical activity | [α]23/D +3.7°, c = 5 in methanol |
| CAS DataBase Reference | 101930-07-8(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| (R)-(+)-1-Benzyl-3-pyrrolidinol Usage And Synthesis |
| Chemical Properties | Colorless to light yellow to gold to brown liquid |
| Uses | (R)-(+)-1-Benzyl-3-pyrrolidinol, is a chiral building block used for the synthesis of various pharmaceutical and biologically active compounds. It can be used for the preparation of beta-proline like derivatives, acting as sodium channel blockers |
| (R)-(+)-1-Benzyl-3-pyrrolidinol Preparation Products And Raw materials |
| Raw materials | Sodium hydroxide-->Hydrochloric acid-->Ethyl acetate-->Methanol-->Tetrahydrofuran-->Dichloromethane-->PETROLEUM ETHER-->Lithium Aluminum Hydride-->Sodium borohydride-->Acetyl chloride-->Calcium chloride-->Benzylamine-->D(+)-Malic acid |
| Preparation Products | (3S)-(-)-3-(DIMETHYLAMINO)PYRROLIDINE |
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