(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID

CAS No.：261165-05-3

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(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Basic information

Product Name:	(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID
Synonyms:	Cyclopentanecarboxylicacid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-, (1S,3R)-;(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID;(+)-(1S,3R)-N-BOC-BETA-HOMOCYCLOLEUCINE;(1S,3R)-(+)-3-(BOC-AMINO)CYCLOPENTANECARBOXYLIC ACID;(1R,3S)-N-TERT-BUTOXYCARBONYL-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID;(-)-(1R,3S)-N-ALPHA-T-BUTOXYCARBONYL-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID;(-)-(1R,3S)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID;(+)-(1R,3S)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID
CAS:	261165-05-3
MF:	C11H19NO4
MW:	229.27
EINECS:
Product Categories:	Unnatural Amino Acid Derivatives;Unusual amino acids;API intermediates;Beta-Amino Acids;Peptide Synthesis
Mol File:	261165-05-3.mol

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Chemical Properties

Melting point	35-49 °C
Boiling point	371.18°C (rough estimate)
density	1.1482 (rough estimate)
refractive index	1.4490 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	slightly sol. in Methanol
form	Powder or Chunks
pka	4.62±0.40(Predicted)
color	White
optical activity	[α]/D +16.0±1°, c = 1% in methanol

Safety Information

Hazard Codes	Xi
Safety Statements	22-24/25
WGK Germany	3
HazardClass	IRRITANT
HS Code	29223900

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Usage And Synthesis

Chemical Properties	white powder or chunks
Uses	(-)-(1R,3S)-N-Boc-1-Aminocyclopentane-3-carboxylic Acid is a reagent used in the synthesis of 3-substituted aminocyclopentanes as potent NR2B subtype-sellective NMDA antagonists in the treatment of neuropathic pain and Parkinson’s.

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

2-Azabicyclo[2.2.1]heptane-2-carboxylic acid, 3-oxo-, 1,1-dimethylethyl ester, (1R,4S)--->(1S,4R)-tert-butyl 3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate-->2-Azabicyclo[2.2.1]heptan-3-one-->(1R,4S)-4-Aminocyclopent-2-enecarboxylic acid-->(1S,3R)-Methyl 3-[(tert-butoxycarbonyl)-amino]cyclopentanecarboxylate-->(1S,3R)-3-Aminocyclopentanecarboxylic acid-->(+)-(1R,4S)-N-BOC-4-AMINOCYCLOPENT-2-ENECARBOXYLIC ACID-->Di-tert-butyl dicarbonate-->2-Azabicyclo[2.2.1]hept-5-en-3-one-->Acetic anhydride

Preparation Products

(+)-(1S,3R)-N-BOC-3-AMINOCYCLOPENTANECARBOXYLIC ACID

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