| 4-(4-Methylpiperazino)aniline Basic information |
| Product Name: | 4-(4-Methylpiperazino)aniline |
| Synonyms: | OTAVA-BB BB7110920492;AKOS BB-8657;AKOS B021941;4-(4-METHYLPIPERAZINO)ANILINE;4-(4-METHYLPIPERAZINE)ANILINE;4-(4-METHYLPIPERAZIN-1-YL)PHENYLAMINE;4-(4-METHYLPIPERAZIN-1-YL)ANILINE;1-(4-AMINOPHENYL)-4-METHYLPIPERAZINE |
| CAS: | 16153-81-4 |
| MF: | C11H17N3 |
| MW: | 191.27 |
| EINECS: | |
| Product Categories: | Phenyls & Phenyl-Het;Piperazines;Phenyls & Phenyl-Het;Piperaizine;API intermediates;Piperazidine intermediates;PIPERIDINE;Amines and Anilines;Heterocycles;Amines |
| Mol File: | 16153-81-4.mol |
| 4-(4-Methylpiperazino)aniline Chemical Properties |
| Melting point | 89 °C |
| Boiling point | 180°C/5mmHg(lit.) |
| density | 1.092±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 8.08±0.42(Predicted) |
| color | Very Dark Gray to Black |
| Sensitive | Air Sensitive |
| CAS DataBase Reference | 16153-81-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | 3259 |
| Hazard Note | Corrosive |
| HazardClass | 8 |
| PackingGroup | III |
| HS Code | 29349990 |
| MSDS Information |
| 4-(4-Methylpiperazino)aniline Usage And Synthesis |
| Chemical Properties | Purple solid |
| Uses | 4-(4-Methylpiperazino)aniline is a reagent in the preparation of benzyloxypyridinone derivative which has c-Met kinase inhibitor properties. |
| 4-(4-Methylpiperazino)aniline Preparation Products And Raw materials |
| Raw materials | Ethyl acetate-->Methanol-->N,N-Dimethylformamide-->Potassium carbonate-->Chloroform-->Dimethyl sulfoxide-->4-Chloronitrobenzene-->1-Methylpiperazine-->Palladium hydroxide |
| Preparation Products | Olmutinib |
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