Other grades of this product :
| FRIEDELIN Basic information |
| Product Name: | FRIEDELIN | | Synonyms: | FRIEDELAN-3-ONE;FRIEDELIN;DA-FRIEDOOLEANAN-3-ONE;FRIEDELIN, TECH.;FRIEDELIN hplc;FRIEDELIN WITH HPLC;DA-friedooleanan-3-one, Friedelan-3-one;D:A-Friedooleanan-3-one (van) (8ci)(9ci) | | CAS: | 559-74-0 | | MF: | C30H50O | | MW: | 426.72 | | EINECS: | 209-205-1 | | Product Categories: | Tri-Terpenoids | | Mol File: | 559-74-0.mol |
| FRIEDELIN Chemical Properties |
| Melting point | 262-265 °C (lit.) | | alpha | D -27.8° (chloroform) | | Boiling point | 477.2±13.0 °C(Predicted) | | density | 0.963±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | neat | | color | White to Off-White | | Merck | 13,4293 | | BRN | 1916451 |
| FRIEDELIN Usage And Synthesis |
| Uses | Friedelin is a flavonoid extract which displays radical scavenging and anti-typhoid activity. | | Uses | Friedelin can be used as a starting material in the synthesis of:- Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
- Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
- Its 1,4-pyrazine derivatives as potent antimicrobial agents.
| | General Description | Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia?avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor?(H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent. |
| FRIEDELIN Preparation Products And Raw materials |
| Raw materials | 6β,27-Dihydroxy-D:A-friedooleanan-3-one-->6β-Hydroxy-D:A-friedooleanan-3-one-->Kokoonol-->21-hydroxyfriedelan-3-one-->24,25,26-Trinoroleanan-3-one, 5,9,13-trimethyl-, (4α,5β,8α,9β,10α,13α,14β)--->3,4-Seco-3,4-epoxyfriedelane-3-one |
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