Tetrabutylammonium fluoride

Tetrabutylammonium fluoride
  • CAS No.:429-41-4
Other grades of this product :
Tetrabutylammonium fluoride Basic information
Product Name:Tetrabutylammonium fluoride
Synonyms:TETRA-N-BUTYLAMMONIUM FLUORIDE: 75% W/W AQUEOUS SOLUTION;TETRABUTYL AMMONIUM FLUORIDE IN THF (I M);Tetrabutylammonium fluoride;TETRA BUTYL AMMONIUM FLUORIDE (1M SOLUTION IN THF);TBAF;TETRABUTYLAMMONIUM FLUORIDE HYDRATE;Tetra-n-butylammonium fluoride, 75% w/w aq. soln.;Tetrabutylammonium Fluoride (1mol/L in Tetrahydrofuran) [for Catalyst of acylation, silylation and cleavage of Silyl Ether]
CAS:429-41-4
MF:C16H36FN
MW:261.46
EINECS:207-057-2
Product Categories:metal halide;quarternary ammonium salts;Reagents;Silica Gel;Supported Synthesis;Fluoride SourcesSupported Synthesis;Ammonium Fluorides (Quaternary);Fluorinating Reagents;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Nucleophilic Fluorinating Reagents;Deprotecting Reagents;Others;Protection and Derivatization;Supported Reagents;Fluorination;Halogenation;Quaternary Ammonium Compounds;Synthetic Organic Chemistry;bc0001
Mol File:429-41-4.mol
Tetrabutylammonium fluoride Chemical Properties
Melting point 62-63 °C(lit.)
density 0.953 g/mL at 25 °C
refractive index n20/D 1.456
Fp 1 °F
storage temp. 2-8°C
solubility Miscible with terahydrofuran, acetonitrile, dimethyl sulfoxide and organic solvents.
form Solution
color Clear light greenish to brown
Water Solubility Insoluble in water.
Sensitive Hygroscopic
Merck 14,9187
BRN 3570522
Exposure limitsACGIH: TWA 2.5 mg/m3NIOSH: IDLH 250 mg/m3
CAS DataBase Reference429-41-4(CAS DataBase Reference)
EPA Substance Registry System1-Butanaminium, N,N,N-tributyl-, fluoride (429-41-4)
Safety Information
Hazard Codes C,F,Xi
Risk Statements 34-19-11-36/37/38-40-37
Safety Statements 26-27-36/37/39-45-33-29-16-36
RIDADR UN 3261 8/PG 2
WGK Germany 3
3
Hazard Note Flammable/Irritant
TSCA Yes
HazardClass 3
PackingGroup II
HS Code 29239000
MSDS Information
ProviderLanguage
TBAF English
SigmaAldrich English
Tetrabutylammonium fluoride Usage And Synthesis
Chemical PropertiesClear light greenish to amber or brown solution
UsesCatalyst for etherification of alcohols and phenols with alkyl halides Catalyst for benzylation reactions.
UsesTetrabutylammonium fluoride is a reagent in organic syntheses in addition, condensation, base-catalyzed cyclization reactions, fluorination and desulfonylation reactions and as a deprotecting agent. Typically dried prior to use.
UsesTetrabutylammonium fluoride (TBAF) is a commonly used organic soluble fluoride salt. It is used as a base, a phase transfer catalyst, and as a fluoride source. In the research field of fluoride sensor development, TBAF is used as an easy to handle and measurable fluoride anion source. The fluoride in TBAF, once dissolved, can be thought of as a free fluoride with little interaction with the ammonium cation. Since TBAF should not absorb light at wavelengths greater than 240nm, it is useful to monitor sensing reactions with visible spectroscopy.
DefinitionChEBI: Tetrabutylammonium fluoride is a fluoride salt and a tetrabutylammonium salt. It has a role as a phase-transfer catalyst.

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