Product

Sulfamonomethoxine

CAS No.：1220-83-3

Other grades of this product :

Sulfamonomethoxine Basic information

Product Name:	Sulfamonomethoxine
Synonyms:	4-azanyl-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide;Sulfamonomethoxine,4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide;4-Methoxy-6-sulfanilaMidopyriMidine;4-SulfanilaMido-6-MethoxypyriMidine;6-Methoxy-4-sulfanilaMidopyriMidine;4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide N-(6-Methoxy-4-pyrimidinyl)sulfanilamide;ici32525;n(sup1)-(6-methoxy-4-pyrimidinyl)-sulfanilamid
CAS:	1220-83-3
MF:	C11H12N4O3S
MW:	280.3
EINECS:	624-483-8
Product Categories:	Heterocycles;Sulfur & Selenium Compounds;Heterocyclic Compounds;Amines;Aromatics;PROSULFA;Inhibitor
Mol File:	1220-83-3.mol

Sulfamonomethoxine Chemical Properties

Melting point	203-2060C
Boiling point	513℃
density	1.3936 (rough estimate)
refractive index	1.6200 (estimate)
Fp	>110°(230°F)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	methanol: soluble10mg/mL
pka	pKa 5.94 (Uncertain)
form	powder
color	white to white with yellow cast
Water Solubility	Soluble in water at 10mg/ml with warming. Also soluble in ethanol or methanol
BRN	621128
CAS DataBase Reference	1220-83-3(CAS DataBase Reference)
EPA Substance Registry System	Sulfamonomethoxine (1220-83-3)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38-43
Safety Statements	26-36
WGK Germany	2
RTECS	WP0550000
HazardClass	IRRITANT
HS Code	29350090
Toxicity	LD50 oral in rabbit: > 10gm/kg

MSDS Information

Provider	Language
SigmaAldrich	English

Sulfamonomethoxine Usage And Synthesis

Chemical Properties	White To Off-White Crystalline Powder
Uses	Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim
Uses	antibacterial
Uses	Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.
Synthesis Reference(s)	The Journal of Organic Chemistry, 26, p. 2764, 1961 DOI: 10.1021/jo01066a034
General Description	Chemical structure: sulfonamide
Biochem/physiol Actions	Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.

Sulfamonomethoxine Preparation Products And Raw materials

Raw materials

Diethyl malonate-->Trichloroethylene-->MALONIC ACID DI-N-BUTYL ESTER-->4-nitrobenzenediazonium chloride-->4-Nitrobenzenesulfonyl chloride

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873