4-Hydroxy-6-methyl-2-pyrone

4-Hydroxy-6-methyl-2-pyrone
  • CAS No.:675-10-5
Other grades of this product :
4-Hydroxy-6-methyl-2-pyrone Basic information
Product Name:4-Hydroxy-6-methyl-2-pyrone
Synonyms:4-hydroxy-6-methyl-2h-pyran-2-on;6-methyl-4-hydroxypyron-(2);triaceticacidlactone;Triacetate lactone;6-Methy-4-hydroxy-2-pyrones;4-Hydroxy-6-Methylpyran-2-one, 97+%;Hydroxy-6-Methyl-2-;NSC 34625
CAS:675-10-5
MF:C6H6O3
MW:126.11
EINECS:211-619-2
Product Categories:Building Blocks;Carbonyl Compounds;API intermediates;Chemical Synthesis;Lactones;Organic Building Blocks
Mol File:675-10-5.mol
4-Hydroxy-6-methyl-2-pyrone Chemical Properties
Melting point 188-190 °C (dec.) (lit.)
Boiling point 174.21°C (rough estimate)
density 1.2048 (rough estimate)
refractive index 1.4189 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 8.6g/l
form Powder
pka5.14±0.30(Predicted)
color Off-white to brown
Water Solubility 8.60 g/L (20 ºC)
BRN 113815
CAS DataBase Reference675-10-5(CAS DataBase Reference)
EPA Substance Registry System2H-Pyran-2-one, 4-hydroxy-6-methyl- (675-10-5)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
RTECS UQ1000000
Hazard Note Irritant
TSCA Yes
HS Code 29322980
MSDS Information
ProviderLanguage
4-Hydroxy-6-methyl-2-pyrone English
SigmaAldrich English
ACROS English
ALFA English
4-Hydroxy-6-methyl-2-pyrone Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses4-Hydroxy-6-methylpyran-2-one was used in the synthesis of pyrano[3,2-c]pyridones with antiproliferative and apoptosis inducing activities. It was also used in the design of benzisothiazolone human leukocyte elastase inhibitors.
Synthesis Reference(s)Synthetic Communications, 20, p. 1931, 1990 DOI: 10.1080/00397919008053123

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