| Chlorodifluoroacetic acid ethyl ester Basic information |
| Product Name: | Chlorodifluoroacetic acid ethyl ester |
| Synonyms: | Ethyl chlorodifluoroacetate 98%;Ethyl 2-chloro-2,2-difluoroacetate;Ethyl chlorodifluoroethanoate;Difluorochloroacetic acid ethyl ester;Ethyl chlorodifluoroacetate, Chlorodifluoroacetic acid ethyl ester;Ethyl 2-chloro-2,2-difluoroethanoate, Chloro(difluoro)acetic acid ethyl ester;Ethyl chloroacetatetwo fluorine;Acetic acid,2-chloro-2,2-difluoro-, ethyl ester |
| CAS: | 383-62-0 |
| MF: | C4H5ClF2O2 |
| MW: | 158.53 |
| EINECS: | 206-850-0 |
| Product Categories: | C2 to C5;Carbonyl Compounds;Fluorinated Building Blocks;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Synthetic Organic Chemistry;Esters;Pharmaceutical Intermediates |
| Mol File: | 383-62-0.mol |
| Chlorodifluoroacetic acid ethyl ester Chemical Properties |
| Boiling point | 96-97.5 °C (lit.) |
| density | 1.252 g/mL at 25 °C (lit.) |
| refractive index | n |
| Fp | 65 °F |
| storage temp. | 2-8°C |
| form | clear liquid |
| Specific Gravity | 1.252 |
| color | Colorless to Almost colorless |
| Sensitive | Moisture Sensitive |
| BRN | 1761413 |
| CAS DataBase Reference | 383-62-0(CAS DataBase Reference) |
| EPA Substance Registry System | Acetic acid, chlorodifluoro-, ethyl ester (383-62-0) |
| Safety Information |
| Hazard Codes | F,C,Xi |
| Risk Statements | 11-34-20/21/22 |
| Safety Statements | 16-26-27-36/37/39-45 |
| RIDADR | UN 2924 3/PG 2 |
| WGK Germany | 3 |
| Hazard Note | Flammable |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29159000 |
| MSDS Information |
| Provider | Language |
|---|---|
| Chlorodifluoroacetic acid ethyl ester | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Chlorodifluoroacetic acid ethyl ester Usage And Synthesis |
| Chemical Properties | clear colorless liquid |
| Uses | Ethyl chlorodifluoroacetate (ECDFA) may be used as a starting reagent in the synthesis of 3-gem-difluoro-2-ethoxy allylic alcohols. |
| General Description | Ethyl chlorodifluoroacetate (ECDFA) undergoes Reformatskii reaction with various aldehydes in DMF. It reacts with phenylacetylene to afford ethyl α,α?difluoro-4-phenyl-3-butenoates. |
| Chlorodifluoroacetic acid ethyl ester Preparation Products And Raw materials |
| Preparation Products | 6-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXALDEHYDE-->1-Bromo-4-(2,2,2-trifluoroethyl)benzene |
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