Product

1-(2-CYANOPHENYL)PIPERAZINE

CAS No.：111373-03-6

Other grades of this product :

1-(2-CYANOPHENYL)PIPERAZINE Basic information

Product Name:	1-(2-CYANOPHENYL)PIPERAZINE
Synonyms:	RARECHEM AH CK 0076;1-(2-CYANOPHENYL)PIPERAZINE;1-(2-CYANPHENYL)-PIPERAZINE;2-(1-Piperazino)benzonitrile;Cyanophenylpiperazine;2-piperazin-1-ylbenzonitrile;1-(2-Cyanophenyl)piperazine 97%;Benzonitrile, 2-(1-piperazinyl)- (9CI)
CAS:	111373-03-6
MF:	C11H13N3
MW:	187.24
EINECS:
Product Categories:	Piperaizine;Building Blocks;Amines and Anilines;Boron, Nitrile, Thio,& TM-Cpds;Heterocyclic Building Blocks;Piperazines;PIPERIDINE
Mol File:	111373-03-6.mol

1-(2-CYANOPHENYL)PIPERAZINE Chemical Properties

Melting point	113-115
Boiling point	314-315 °C (lit.)
density	1.115 g/mL
refractive index	n20/D 1.5890(lit.)
Fp	118 °F
pka	8.77±0.10(Predicted)
form	clear liquid
Specific Gravity	1.115
color	Colorless to Light orange to Yellow
Sensitive	Moisture Sensitive
BRN	785973
CAS DataBase Reference	111373-03-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	10-36
Safety Statements	16-24/25-36
RIDADR	UN 1993 3/PG 3
WGK Germany	3
Hazard Note	Irritant
HazardClass	8
PackingGroup	II
HS Code	2933599590

MSDS Information

Provider	Language
SigmaAldrich	English
ALFA	English

1-(2-CYANOPHENYL)PIPERAZINE Usage And Synthesis

Uses	1-(2-cyanophenyl)piperazine is used in the synthesis of melanocortin subtype-4 receptor (MC4R) agonists. MC4R is located in the hypothalamus and helps to regulate metabolism, feeding and reproductive behavior. Agonists to these receptors have shown to decrease feeding behaviors.

1-(2-CYANOPHENYL)PIPERAZINE Preparation Products And Raw materials

Raw materials

Ethyl acetate-->Diethyl ether-->Dichloromethane-->Toluene-->Potassium carbonate-->Dimethyl sulfoxide-->Di-tert-butyl dicarbonate-->Piperazine-->2-Bromobenzonitrile-->2-Fluorobenzonitrile-->2-methylpentane-->1-(2-iodophenyl)piperazine-->1-(2-BROMOPHENYL)PIPERAZINE-->TERT-BUTYL 4-(2-CYANOPHENYL)PIPERAZINE-1-CARBOXYLATE-->Nornitrogen mustard-->Bis(2-chloroethyl)amine hydrochloride-->2-Aminobenzonitrile

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