Product

Phthaloyl amlodipine

CAS No.：88150-62-3

Other grades of this product :

Phthaloyl amlodipine Basic information

Product Name:	Phthaloyl amlodipine
Synonyms:	3-ethyl 5-methyl 4-(2-chlorophenyl)-1,4-dihydro-2-[2-(1,3-dihydro-1,3-dioxo-(2H)isoindol-2-yl)-ethoxymethyl]-6-methyl-3,5-pyridinedicarboxylate;1-Amino-6-fluoro-1,4-dihydro-7-(4-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl)piperazin-1-yl)-4-oxo-[1,3]thiazeto[3,2-A]quinoline-3-carboxylic acid;3-Ethyl-5-methyl-4-(2-chlorophenyl)-2-(2-phthalimidoethoxyl)methyl-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-(phthalimidoethoxy)methyl-1,4-dihydropyridine;Phthalimidoamlodipine;3,5-Pyridinedicarboxylicacid,4-(2-chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]Methyl]-1,4-dihydro-6-Methyl-,3-ethyl 5-Methyl ester;4-(2-Chlorophenyl)-3-Ethoxy carbonyl-5-Methoxy carbonil-6-Methyl-2-(phthaliMidoethoxy)Methyl-1,4-dihydropyridine;4-(2-Chlorophenyl)-2-[[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]Methyl]-1,4-dihydro-6-Methyl-3,5-pyridinedicarboxylic Acid 3-Ethyl 5-Methyl Ester
CAS:	88150-62-3
MF:	C28H27ClN2O7
MW:	538.98
EINECS:	413-410-3
Product Categories:	API intermediates;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	88150-62-3.mol

Phthaloyl amlodipine Chemical Properties

Melting point	140-145°C
Boiling point	654.1±55.0 °C(Predicted)
density	1.321±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly, Heated and Sonicated)
form	neat
pka	2.06±0.70(Predicted)
color	Pale Yellow to Light Yellow
PH	6.78 at 20.4℃ and 10g/L
LogP	4.9 at 30℃ and pH6.79
CAS DataBase Reference	88150-62-3(CAS DataBase Reference)

Safety Information

Risk Statements	53
Safety Statements	61
HS Code	2933399090

MSDS Information

Phthaloyl amlodipine Usage And Synthesis

Chemical Properties	Pale Yellow Solid
Uses	Amilodopine intermediate
Uses	Amlodipine intermediate. Amlodipine Related Compound A
Uses	Amlodipine intermediate.

Phthaloyl amlodipine Preparation Products And Raw materials

Raw materials

N-Hydroxyethylphthalimide-->2-Acetyl-3-(2-chlorophenyl)acrylic acid methyl ester-->methyl 3-aminocrotonate-->ETHYL4-[2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ETHOXYL]-3-OXOBUTANOATE-->2-[(2-Chlorophenyl)Methylene]-4-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Ethyl Ester-->Ethyl 4-chloroacetoacetate-->Methyl 3-aminocrotonate

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