Carzenide

CAS No.：138-41-0

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Carzenide Basic information

Product Name:	Carzenide
Synonyms:	P-CARBOXYBENZENESULFONAMIDE;4-(aminosulfonyl)-benzoicaci;Benzoic acid, 4-(aminosulfonyl)-;Benzoic acid, p-sulfamoyl-;Carzenid;Dirnate;4-sulphamoylbenzoic acid;p-Caroxybenzenesulfonamide
CAS:	138-41-0
MF:	C7H7NO4S
MW:	201.2
EINECS:	205-327-4
Product Categories:	138-41-0
Mol File:	138-41-0.mol

Carzenide Chemical Properties

Melting point	285-295 °C (lit.)
Boiling point	449.0±47.0 °C(Predicted)
density	1.5083 (rough estimate)
refractive index	1.6100 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	0.5g/l
form	Powder
pka	3.50(at 25℃)
color	White
Water Solubility	453 mg/L (25 ºC)
Merck	14,1876
BRN	1875393
CAS DataBase Reference	138-41-0(CAS DataBase Reference)
NIST Chemistry Reference	P-sulfamoylbenzoic acid(138-41-0)
EPA Substance Registry System	4-Aminosulfonylbenzoic acid (138-41-0)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	36/37/38-20/21/22
Safety Statements	22-24/25-36/37/39-26-36
WGK Germany	3
RTECS	DH6820000
TSCA	Yes
HazardClass	IRRITANT
HS Code	29163990
Toxicity	LD50 i.p. in rats: 350 ± 22 mg/kg (Appenroth, Brunlich)

MSDS Information

Provider	Language
Carzenide	English
SigmaAldrich	English
ACROS	English
ALFA	English

Carzenide Usage And Synthesis

Chemical Properties	White powder
Uses	diuretic, carbonic anhydrase inhibitor
Uses	4-Sulfamoylbenzoic Acid is used as a reagent in the synthesis of carbonic anhydrase inhibitors anticonvulsant agents.

Carzenide Preparation Products And Raw materials

Raw materials	Potassium dichromate-->p-Toluenesulfonamide
Preparation Products	4-CYANOBENZENESULFONYL CHLORIDE 97-->4-SULFAMIDOBENZOYL CHLORIDE DMF COMPLEX-->4-(CHLOROSULFONYL)BENZOIC ACID

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