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| TEBIPENEM PIVOXIL Basic information |
| Product Name: | TEBIPENEM PIVOXIL | | Synonyms: | (1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid pivaloyloxymethyl ester;Tebipenem Pivoxil;[(2,2-Dimethylpropanoyl)oxy]methyl (4R,5S,6S)-3-{[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate;(4R,5S,6S)-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (2,2-DiMethyl-1-oxopropoxy)Methyl Ester;[4R-[4α,5β,6β(R*)]]-3-[[1-(4,5-Dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-Methyl-7-oxo-1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid (2,2-DiMethyl-1-oxopropoxy)Methyl Ester;OrapeneM;ME1211;TBPM-PI | | CAS: | 161715-24-8 | | MF: | C22H31N3O6S2 | | MW: | 497.63 | | EINECS: | 1308068-626-2 | | Product Categories: | Inhibitors;API | | Mol File: | 161715-24-8.mol |
| TEBIPENEM PIVOXIL Chemical Properties |
| Melting point | 140-142℃ | | Boiling point | 661.9±65.0 °C(Predicted) | | density | 1.50 | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 14.36±0.20(Predicted) | | form | Solid | | color | White |
| TEBIPENEM PIVOXIL Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Tebipenem Pivoxil is an oral carbapenem antibiotic. Tebipenem Pivoxil is absorbed and metabolized into Tebipenem, its active metabolite which showed excellent bactericidal activity against β-lactamase
-nonproducing, ampicillin-resistant isolates. | | Uses | Tebipenem Pivoxil is an oral carbapenem antibiotic. Tebipenem Pivoxil is absorbed and metabolized into Tebipenem, its active metabolite which showed excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates. | | Uses | Tebipenem pivoxil(L-084) is a novel oral carbapenem antibiotic with an IC50 of 100 μg/ml for human CYP isoforms. In mouse, rat, dog and monkey, TBPM-PI were absorbed quickly, and the bioavailability was (71.4, 59.1, 34.8 and 44.9%, respectively. There was |
| TEBIPENEM PIVOXIL Preparation Products And Raw materials |
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