Product

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester

CAS No.：1334513-02-8

Other grades of this product :

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Basic information

Product Name:	N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
Synonyms:	1. (S)-isopropyl2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl);N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester　(SIDE CHAIN);L-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester;propan-2-yl (2S)-2-{[(S)-pentafluorophenoxy(phenoxy)phosphoryl]amino}propanoate;Sofosbuvir side chain N-1;Sofosbuvir Intermediate 5;isopropyl ((S)-(perfluorophenoxy)(phenoxy)phosphoryl)-L-alaninate;N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester
CAS:	1334513-02-8
MF:	C18H17F5NO5P
MW:	453.3
EINECS:	695-076-0
Product Categories:	Sofosbuvir intermediate;Pharmaceuticalintermediates
Mol File:	1334513-02-8.mol

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Chemical Properties

Melting point	133-135°C
Boiling point	442.6±55.0 °C(Predicted)
density	1.405
vapor pressure	0Pa at 25℃
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	-3.81±0.70(Predicted)
form	Solid
color	White
LogP	4.1 at 30℃ and pH7.37

Safety Information

HS Code

2931599090

MSDS Information

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Usage And Synthesis

Uses	N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is a reactant in the synthesis of phosphoramidate imidazo[2,1-f][1,2,4]triazine-4-amine adenosine prodrugs that can increase anti-HCV activity.

N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl ester Preparation Products And Raw materials

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