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| N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Basic information |
| N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Chemical Properties |
| Melting point | 96.1-98.3°C | | Boiling point | 479.9±45.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | methanol: 0.1 g/mL, clear, yellow | | pka | 13.02±0.70(Predicted) | | form | Solid | | color | White Waxy | | BRN | 6057483 | | CAS DataBase Reference | 85618-20-8(CAS DataBase Reference) |
| N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Usage And Synthesis |
| Chemical Properties | White Paste | | Uses | n-Heptyl β-D-thioglucopyranoside is useful non-ionic detergent for solubilization and reconstitution of membrane proteins of Escherichia coli.
| | Purification Methods | The tetraacetyl derivative is purified by silica gel column chromatography and eluted with a *C6H6/Me2CO gradient (up to 5% of Me2CO) and recrystallises from n-hexane as colourless needles m 72-74o (Erbing & Lindberg Acta Chem Scand B30 611 1976 gave m 69-70o). Hydrolysis with an equivalent of base in methanol gives the desired glucoside. This is a non-ionic detergent for reconstituting membrane proteins and has a critical micelle concentration of 30 mM. [Shimamoto et al. J Biochem (Tokyo) 97 1807 1985; Saito & Tsuchiya Chem Pharm Bull Jpn 33 503 1985]. |
| N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Preparation Products And Raw materials |
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