Other grades of this product :
| Indole-6-carboxylic acid Basic information |
| Indole-6-carboxylic acid Chemical Properties |
| Melting point | 249-253 °C(lit.) | | Boiling point | 287.44°C (rough estimate) | | density | 1.2480 (rough estimate) | | refractive index | 1.5050 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 4.44±0.30(Predicted) | | form | Powder | | color | Yellow-beige to orange-brown | | BRN | 123991 | | CAS DataBase Reference | 1670-82-2(CAS DataBase Reference) |
| Indole-6-carboxylic acid Usage And Synthesis |
| Chemical Properties | yellow-beige to orange-brown powder | | Uses | • ;Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase1• ;Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors2• ;Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway3• ;Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity4• ;Reactant for preparation of pyridinyl carboxylates via esterification with chlorohyd | | Uses | Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase ? Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors ? Reactant for preparation of amide conju | | Uses | - Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase
- Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
- Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
- Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity
- Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors
- Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors
| | Synthesis Reference(s) | Journal of Medicinal Chemistry, 35, p. 2419, 1992 DOI: 10.1021/jm00091a010 |
| Indole-6-carboxylic acid Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye