ISOQUERCITRIN

ISOQUERCITRIN
  • CAS No.:482-35-9
Other grades of this product :
ISOQUERCITRIN Basic information
Product Name:ISOQUERCITRIN
Synonyms:anosyloxy)-;Isoquercitrin/Isoquercetin;glucosyl3-quercetin;hirsutrin;quercetin3-beta-glucoside;quercetin3-beta-o-glucoside;quercetin3-d-glucoside;quercetin3-monoglucoside
CAS:482-35-9
MF:C21H20O12
MW:464.38
EINECS:640-533-1
Product Categories:Antineoplastic
Mol File:482-35-9.mol
ISOQUERCITRIN Chemical Properties
Melting point 230 °C
Boiling point 872.6±65.0 °C(Predicted)
density 1.87±0.1 g/cm3(Predicted)
FEMA 4225 | ISOQUERCITRIN, ENZYMATICALLY MODIFIED
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form neat
pka6.17±0.40(Predicted)
color Light Yellow to Yellow
BRN 100989
Stability:Hygroscopic
InChIKeyOVSQVDMCBVZWGM-QSOFNFLRSA-N
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
RTECS LK8960000
10-23
HS Code 29389090
ToxicityLD50 intraperitoneal in mouse: > 5gm/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
ISOQUERCITRIN Usage And Synthesis
Chemical PropertiesWhite to Light Yellow Powder
UsesIsoquercitrin was used as standard to compare the retention time of samples for identifying chromatographic peaks during flavonoid identification by Orbitrap UHPLC-MS/MS analysis.
UsesQuercetin 3-β-D-glucoside has been used:
  • as a dietary flavonoid supplement to check its binding capacity with human small ubiquitin-related modifier 1 (SUMO1) protein using surface plasmon resonance (SPR)
  • as an inhibitor for Escherichia coli adenosine triphosphate (ATP) synthase
  • as an anti-aggregation agent to test its activity against β-amyloid, green fluorescent protein?(GFP), and chymotrypsinogen proteins
General DescriptionProduced and qualified by HWI pharma services GmbH.Exact content by quantitative NMR can be found on the certificate.
Biochem/physiol ActionsQuercetin 3-β-D-glucoside possesses strong antioxidant and anti-inflammatory activities. Being a potent oxygen-radical scavenger, it is a neuroprotective agent that improves Alzheimer′s disease (AD) condition in mice models. It has shown antiproliferative activity against colon, lung, and hepatocellular cell lines and MCF-7 human breast cancer cells in combination with apple extracts.
ISOQUERCITRIN Preparation Products And Raw materials

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