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| 6-Chloro-2-fluoropurine Basic information |
| 6-Chloro-2-fluoropurine Chemical Properties |
| Melting point | 162-163°C | | Boiling point | 221.8±50.0 °C(Predicted) | | density | 1.98±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 4.88±0.20(Predicted) | | color | White to Light yellow to Green | | CAS DataBase Reference | 1651-29-2(CAS DataBase Reference) |
| 6-Chloro-2-fluoropurine Usage And Synthesis |
| Description | 6-Chloro-2-fluoropurine is a heterocyclic building block. It has been used in the synthesis of purine nucleosides that inhibit cyclin-dependent kinases (CDKs) in vitro. 6-Chloro-2-fluoropurine has also been used in the synthesis of purine nucleosides that are active against HIV-1 and hepatitis B virus (HBV) in vitro. | | Chemical Properties | Beige solid | | Uses | 6-Chloro-2-fluoropurine is used as a reagent in the synthesis of several organic compounds including that of 2''-Fluoro-3''-Hydroxymethyl-5''-deoxythreosyl phosphonic acid nucleoside analogues which may potentially act as antiviral agents. It is also used in the synthesis of 2'',5'',5''-trifluoro-3''-hydroxy-apiosyl nucleoside phosphonic acid analogues which may possess potent anti-HCMV properties. |
| 6-Chloro-2-fluoropurine Preparation Products And Raw materials |
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