| Methyl diethylphosphonoacetate Basic information |
| Product Name: | Methyl diethylphosphonoacetate |
| Synonyms: | Diethyl methoxycarbonylmethanephosphonate for synthesis;Acetic acid, (diethoxyphosphinyl)-, methyl ester;Diethyl carbomethoxymethylphosphonate;Methyl (diethoxyphosphoryl)acetate;APAZ-027;METHYL P,P-DIETHYLPHOSPHONOACETATE;METHYL DIETHYLPHOSPHONOACETATE;LABOTEST-BB LT00452673 |
| CAS: | 1067-74-9 |
| MF: | C7H15O5P |
| MW: | 210.16 |
| EINECS: | 213-938-2 |
| Product Categories: | Horner-Emmons Reaction;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction |
| Mol File: | 1067-74-9.mol |
| Methyl diethylphosphonoacetate Chemical Properties |
| Boiling point | 127-131 °C9 mm Hg(lit.) |
| density | 1.145 g/mL at 25 °C(lit.) |
| refractive index | n |
| Fp | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Miscible with tetrahydrofuran. |
| form | Liquid |
| color | Clear colorless to faint yellow |
| BRN | 1782397 |
| CAS DataBase Reference | 1067-74-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, phosphono-, p,p-diethyl c-methyl ester(1067-74-9) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 10 |
| HS Code | 29310095 |
| MSDS Information |
| Provider | Language |
|---|---|
| Methyl diethylphosphonoacetate | English |
| ACROS | English |
| SigmaAldrich | English |
| ALFA | English |
| Methyl diethylphosphonoacetate Usage And Synthesis |
| Chemical Properties | Clear colorless to slightly yellow liquid |
| Uses | Methyl diethylphosphonoacetate is used as a reagent in the preparation of allylic fluorides compounds and in regioselective Diels-Alder reactions. It also serves as a reactant in the preparation of substituted thiophenes and furans, which finds application in type 2 diabetes treatment. Further, it acts as a precursor in the synthesis of pyridone alkaloids and immunosuppressive cyclopentanediol derivatives. In addition to this, it is utilized in the modification of botulinum neurotoxin serotype A protease inhibitors. |
| Methyl diethylphosphonoacetate Preparation Products And Raw materials |
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