3,4-Dimethoxy-L-phenylalanine

CAS No.：32161-30-1

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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3,4-Dimethoxy-L-phenylalanine Basic information

Product Name:	3,4-Dimethoxy-L-phenylalanine
Synonyms:	(S)-3,4-DIMETHOXY-PHENYLALANINE;(S)-2-AMINO-3-(3,4-DIMETHOXY-PHENYL)-PROPIONIC ACID;TYROSINE, 3-METHOXY-O-METHYL-;3,4-DIMETHOXY-L-PHENYLALANINE;H-PHE[3,4-(OME) 2]-OH;H-PHE(3,4-DIMETHOXY)-OH;H-TYR(3-OME,4-ME)-OH;H-3,4-DIMETHOXY-PHE-OH
CAS:	32161-30-1
MF:	C11H15NO4
MW:	225.24
EINECS:	626-580-0
Product Categories:	Amino Acids & Derivatives;Aromatics;Peptide Synthesis;Phenylalanine Derivatives;Unnatural Amino Acid Derivatives
Mol File:	32161-30-1.mol

3,4-Dimethoxy-L-phenylalanine Chemical Properties

Melting point	254-257 °C(lit.)
alpha	-5 º (c=4 in 1 M HCl)
Boiling point	374.3±42.0 °C(Predicted)
density	1.214±0.06 g/cm3(Predicted)
storage temp.	Store at 0°C
solubility	Aqueous Acid (Slightly, Heated Sonicated), Aqueous Base (Slightly), Water (Sligh
form	Solid
pka	2.23±0.20(Predicted)
color	White to Off-White
optical activity	[α]22/D 5°, c = 4 in 1 M HCl
Sensitive	Air Sensitive
Stability:	Hygroscopic, Temperature Sensitive
CAS DataBase Reference	32161-30-1(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37
WGK Germany	3
HS Code	29224999

MSDS Information

Provider	Language
SigmaAldrich	English

3,4-Dimethoxy-L-phenylalanine Usage And Synthesis

Chemical Properties	White Solid
Uses	DOPA intermediate.
Uses	3-(3,4-Dimethoxyphenyl)-L-alanine can be used as a reactant to synthesize (2S)-2-amino-3-[3,4-di(methoxy)phenyl]propan-1-ol (β-amino alcohol) for use as a key intermediate to prepare tetracyclic core of the Erythrina alkaloids.
Uses	DOPA intermediate

3,4-Dimethoxy-L-phenylalanine Preparation Products And Raw materials

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