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| 2,5-Dichloropyridine Basic information | | Uses |
| Product Name: | 2,5-Dichloropyridine | | Synonyms: | 2,5-Dichloropyridine, 98% 5GR;2,5- twochlorine pyridine;2,5-Dichiloropyridine;2,5-Chloro pyridine;2,5-dichloro-pyridin;2,5-DICHLORPYRIDINE;2,5-Dichloropyridine97%;Dichloropyridine | | CAS: | 16110-09-1 | | MF: | C5H3Cl2N | | MW: | 147.99 | | EINECS: | 240-278-2 | | Product Categories: | Chlorinated heterocyclic series;Pyridines, Pyrimidines, Purines and Pteredines;Halides;Pyridines;Chloropyridines;Halopyridines;Pyridine;pyridine derivative;Boronic Acid;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Building Blocks;C5;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;alkyl chloride;bc0001 | | Mol File: | 16110-09-1.mol |
| 2,5-Dichloropyridine Chemical Properties |
| Melting point | 59-62 °C (lit.) | | Boiling point | 190-191 °C | | density | 1.5159 (rough estimate) | | refractive index | 1.5500 (estimate) | | Fp | 112 °C | | storage temp. | Inert atmosphere,Room Temperature | | pka | -2.25±0.10(Predicted) | | form | Crystalline Solid | | color | White to slightly yellow | | Water Solubility | insoluble | | BRN | 108886 | | CAS DataBase Reference | 16110-09-1(CAS DataBase Reference) |
| Hazard Codes | Xi,Xn | | Risk Statements | 36/37/38-22 | | Safety Statements | 26-37/39-36 | | RIDADR | UN2811 | | WGK Germany | 3 | | RTECS | US8225000 | | Hazard Note | Harmful | | HazardClass | IRRITANT | | HazardClass | 6.1 | | HS Code | 29333990 |
| 2,5-Dichloropyridine Usage And Synthesis |
| Uses | 2,5-Dichloropyridine is a reagent used in chemical synthesis. It has been used to synthesize 4-benzodiazepine-2,5 diones as Hdm2 antagonists and inhibitors of ERK protein kinase. | | Chemical Properties | white to slightly yellow crystalline solid | | Uses | 2,5-Dichloropyridine was used in the synthesis of 6-halo-pyridin-3-yl boronic acids and esters. It undergoes cross-coupling reaction with arylboronic acids in the presence of [1,4-bis-(diphenylphosphine)butane]palladium (II) dichloride as catalyst. | | Synthesis Reference(s) | Synthetic Communications, 20, p. 2971, 1990 DOI: 10.1080/00397919008051514 | | General Description | 2,5-Dichloropyridine undergoes cross-coupling reaction with arylboronic acids in the presence of [1,4-bis-(diphenylphosphine)butane]palladium (II) dichloride as catalyst. |
| 2,5-Dichloropyridine Preparation Products And Raw materials |
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