N-ACETYLLACTOSAMINE

CAS No.：32181-59-2

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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N-ACETYLLACTOSAMINE Basic information

Product Name:	N-ACETYLLACTOSAMINE
Synonyms:	Glucopyranose Galf1-b-4-GlcNAc;2-Acetamido-2-deoxy-4-O-D-galactopyranosyl-D-glucopyranose, N-Acetyl-4-O-(D-galactopyranosyl)-D-glucosamine;2-Acetamido-2-deoxy-4-O--D-galactopyranosyl-D-glucopyranose;Gal-(1-4)-D-GlcNAc;2-Acetylamino-4-O-β-D-galactopyranosyl-2-deoxy-D-glucopyranose;4-O-(β-D-Galactopyranosyl)-2-(acetylamino)-2-deoxy-D-glucopyranose;4-O-(β-D-Galactopyranosyl)-2-acetylamino-2-deoxy-D-glucopyranose;4-O-β-D-Galactopyranosyl-2-(acetylamino)-2-deoxy-D-glucopyranose
CAS:	32181-59-2
MF:	C14H25NO11
MW:	383.35
EINECS:
Product Categories:	Oligosaccharides;Carbohydrates
Mol File:	32181-59-2.mol

N-ACETYLLACTOSAMINE Chemical Properties

Melting point	191-192
Boiling point	858.1±65.0 °C(Predicted)
density	1.58±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	H₂O: 10 mg/mL, clear, colorless
pka	12.85±0.20(Predicted)
form	Solid
color	White to Pale Beige
BRN	96808
Stability:	Hygroscopic

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37
WGK Germany	3
F	3-10
Hazard Note	Irritant
HS Code	29400090

MSDS Information

Provider	Language
SigmaAldrich	English

N-ACETYLLACTOSAMINE Usage And Synthesis

Chemical Properties	White Crystalline Solid
Uses	A component of oligosaccharide portion of many N- and O-linked glycoproteins. It is a building unit for the antigenic determinants of a number of certain human blood group activities as well as of the ABH Type 2 determinants
Uses	N-Acetyl-D-lactosamine is used as a specific lectin target molecule in the identification and differentiation of sugar binding molecules such as the galectins. N-Acetyl-D-lactosamine is used in studies of galactosidase, fucosyltransferase, sialyltransferase, and lectin inhibition.
Uses	N-Acetyllactosamine is used in the expansion of a multi-funcational natural scaffold for the study of structural space of the Galectin-1-Ligand interaction. Also, it is used to identify the impurity as an imidazoline ring structure.
Purification Methods	Purify N-acetyl-D-lactosamine by recrystallisation from MeOH (with 1 mol of MeOH) or from H2O. It is available commercially as a solution of 0.5g/mL of H2O. [Zilliken J Biol Chem 271 181 1955, Beilstein 17 IV 3452.]

N-ACETYLLACTOSAMINE Preparation Products And Raw materials

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