p-Toluoyl chloride

CAS No.：874-60-2

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

p-Toluoyl chloride Basic information

Product Name:	p-Toluoyl chloride
Synonyms:	4-methylbenzoicacidchloride;4-methyl-benzoylchlorid;Benzoyl chloride, 4-methyl-;p-Toluoyl chlori;p-Toluoyl chloride 98%;The Methyl benzoyl chloride;P-methbenzoylchloride;4-Methylbenzenecarbonyl chloride
CAS:	874-60-2
MF:	C8H7ClO
MW:	154.59
EINECS:	212-864-8
Product Categories:	Acid Halides;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Pyridines;ACIDHALIDE;874-60-2
Mol File:	874-60-2.mol

p-Toluoyl chloride Chemical Properties

Melting point	-4--2 °C (lit.)
Boiling point	225-227 °C (lit.) 95-96 °C/10 mmHg (lit.)
density	1.169 g/mL at 25 °C (lit.)
vapor density	5.33 (vs air)
vapor pressure	0.55 mm Hg ( 20 °C)
refractive index	n20/D 1.553(lit.)
Fp	180 °F
storage temp.	Store below +30°C.
form	Liquid
Specific Gravity	1.169
color	Clear colorless to slightly brown
PH	1 (H2O, 20℃)
explosive limit	1.6%, 117°F
Water Solubility	Reacts with water alcohol.
Sensitive	Moisture Sensitive
BRN	471492
CAS DataBase Reference	874-60-2(CAS DataBase Reference)
NIST Chemistry Reference	4-Methylbenzoic acid chloride(874-60-2)
EPA Substance Registry System	Benzoyl chloride, 4-methyl- (874-60-2)

Safety Information

Hazard Codes	C
Risk Statements	34
Safety Statements	26-36/37/39-45-24/25
RIDADR	UN 3265 8/PG 2
WGK Germany	3
RTECS	XV1660000
TSCA	Yes
HazardClass	8
PackingGroup	II
HS Code	29163900

MSDS Information

Provider	Language
4-Methylbenzoyl chloride	English
SigmaAldrich	English
ACROS	English
ALFA	English

p-Toluoyl chloride Usage And Synthesis

Chemical Properties	CLEAR COLOURLESS TO SLIGHTLY BROWNISH LIQUID
Uses	p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin
Uses	p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin. It is used as a reagent to synthesize (+)-Yashabushitriol, derivatives of Desloratadine.
Uses	Intermediates of Liquid Crystals
General Description	p-Toluoyl chloride causes the benzoylation of toluene using triflic acid funtionalized mesoporous Zr-TMS catalysts. It causes1,9-diacylation of a dipyrromethane using the hindered Grignard reagent 2,6-dimethylphenylmagnesium bromide.

p-Toluoyl chloride Preparation Products And Raw materials

Raw materials	p-Toluic acid-->(4-METHYLPHENYL)-1,2-ETHANEDIOL-->4-Methylbenzyl alcohol-->4-Methyl-benzoic acid tert-butyl ester-->4-Iodobenzoyl chloride-->4-Iodotoluene-->carbon monoxide-->4-Bromotoluene-->4-Iodoanisole-->P-XYLENE-->Butyryl chloride-->Terephthaloyl chloride-->p-Tolualdehyde
Preparation Products	4-METHYLHIPPURIC ACID-->4-(BROMOMETHYL)-N-(L-METHYLETHYL)BENZAMIDE-->2-(4-METHYLPHENYL)-BENZOTHIAZOLE-->p-Tolyl isocyanate-->1-Iodo-4-nitrobenzene-->4-METHYLPHTHALIMIDE 99-->4,N-DIMETHYL-N-METHOXYBENZAMIDE

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873