2-Ethylphenol

2-Ethylphenol
  • CAS No.:90-00-6
Other grades of this product :
2-Ethylphenol Basic information
Product Name:2-Ethylphenol
Synonyms:2-ETHYLPHENOL;PHLOROL;ORTHO-ETHYLPHENOL;O-ETHYLPHENOL;Ethylphenol;o-ethyl-pheno;Phenol, o-ethyl-;Phenol,2-ethyl-
CAS:90-00-6
MF:C8H10O
MW:122.16
EINECS:201-958-4
Product Categories:Alpha sort;E;Phenol&Thiophenol&Mercaptan;E-GAlphabetic;EQ - EZ;Pesticides&Metabolites;Aromatic Phenols;Phenoles and thiophenoles;Organic Building Blocks;Oxygen Compounds;Phenols
Mol File:90-00-6.mol
2-Ethylphenol Chemical Properties
Melting point -18 °C (lit.)
Boiling point 195-197 °C (lit.)
density 1.037 g/mL at 25 °C (lit.)
refractive index n20/D 1.536(lit.)
Fp 78 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pkapK1:10.2 (25°C)
form clear liquid
color Colorless to Light yellow
Water Solubility insoluble
Merck 14,3839
BRN 1099397
Stability:Stable. Combustible. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.
CAS DataBase Reference90-00-6(CAS DataBase Reference)
NIST Chemistry ReferencePhenol, 2-ethyl-(90-00-6)
EPA Substance Registry Systemo-Ethylphenol (90-00-6)
Safety Information
Hazard Codes Xn,Xi,C
Risk Statements 22-37/38-41-34-20/21/22
Safety Statements 36/37/39-45-26
RIDADR UN 3145 8/PG 2
WGK Germany 3
RTECS SL4025000
8
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29071900
Hazardous Substances Data90-00-6(Hazardous Substances Data)
MSDS Information
ProviderLanguage
2-Ethylphenol English
ACROS English
SigmaAldrich English
ALFA English
2-Ethylphenol Usage And Synthesis
Chemical Properties2-Ethylphenol is a colorless liquid. It is one of three isomeric ethylphenols. It has been used as a reagent for the synthesis of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists for the treatment of diabetes mellitus. 2-Ethylphenol has also been used in the preparation of aminoquinazoline-like toll receptor ligands and for potential immunotherapy.
Uses2-Ethylphenol is used as a reagent in the synthesis of phenoxyacetic acid derivatives as novel free fatty acid receptor 1 agonists used in the treatment of diabetes. It is also used in the preparation of aminoquinazolines as Toll-like receptor 4 ligands and potential immunotherapeutics.
DefinitionChEBI: 2-Ethylphenol is a member of phenols.
Preparation2-Ethylphenol is produced by ethylation of phenol using ethylene or ethanol in the presence of aluminium phenolate. It is a natural product found in Cichorium endivia, Saussurea involucrata, and other organisms with data available.
Safety ProfilePoison by intraperitoneal route. Moderately toxic by ingestion. Human toxic action similar to, but less severe than, that of phenol. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also PHENOL
Purification MethodsPurify as for p-ethylphenol below. [Beilstein 6 H 470, 6 IV 3011.]
2-Ethylphenol Preparation Products And Raw materials
Raw materials3-Ethylphenol-->2,3-Dihydrobenzofuran
Preparation Products2-ETHYLCYCLOHEXANONE-->Acridine

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