Other grades of this product :
| L-SEPIAPTERIN Basic information |
| Product Name: | L-SEPIAPTERIN | | Synonyms: | (S)-2-aMino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(1H)-one;(S)-2-AMino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one;Sepiapterin solid;S(-)-2-AMINO-7,8-DIHYDRO-6-(2-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE;SEPIAPTERIN;L-SEPIAPTERIN;L-SEPIAPTERIN DIHYDRATE;2-AMINO-7,8-DIHYDRO-6-(2S-HYDROXY-1-OXOPROPYL)-4(1H)-PTERIDINONE | | CAS: | 17094-01-8 | | MF: | C9H11N5O3 | | MW: | 237.22 | | EINECS: | | Product Categories: | | Mol File: | 17094-01-8.mol |
| L-SEPIAPTERIN Chemical Properties |
| Melting point | >270 °C (dec.) | | Boiling point | 448.1±55.0 °C(Predicted) | | density | 1.86±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO: 27 mg/mL | | pka | 12.33±0.20(Predicted) | | form | solid | | color | yellow | | Stability: | Light Sensitive | | CAS DataBase Reference | 17094-01-8 |
| Safety Statements | 24/25 | | WGK Germany | 3 |
| L-SEPIAPTERIN Usage And Synthesis |
| Chemical Properties | yellow to orange powder | | Uses | L-Sepiapterin serves as a substrate for BH4 synthesis via the pterin salvage pathway. It inhibits rat liver GTP cyclohydrolase with an IC50 value of approximately 25 μM. It can be used to circumvent the inhibition of pterin biosynthesis by 2,4-diamino-6-hydroxy pyrimidine.[Cayman Chemical] | | Uses | Sepiapterin improved the endothelial dysfunction in SMA from db?/db mice by decreasing oxidative stress. Sepiapterin is commonly used in the study for treamtment of Type I Diabetes | | Uses | Sepiapterin can be used to induce sequence-specific photolesions in double-stranded DNA. | | General Description | Sepiapterin, a pteridine derivative, is a stable precursor of tetrahydrobiopterin (BH4). It is a yellow pigment found in sepia mutant of Drosophila melanogaster and lemon Bombyx mori mutant (silkworm). | | Biochem/physiol Actions | Cofactor of nitric oxide synthase; intracellularly converted to tetrahydro-biopterin leading to the stimulation of nitric oxide. |
| L-SEPIAPTERIN Preparation Products And Raw materials |
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