poly(L-lactide)

CAS No.：33135-50-1

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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poly(L-lactide) Basic information

Physical properties Uses

Product Name:	poly(L-lactide)
Synonyms:	POLY[(3S-CIS)-3,6-DIMETHYL 1,4-DIOXANE-2,5-DIONE];PURASORB(R) PL2;PURASORB(R) PL4;PURASORB(R) PL6;PURASORB(R) PL8;PURASORB(R) PL;PURASORB(R) PL10;L-LACTIDE POLYMER
CAS:	33135-50-1
MF:	C6H8O4
MW:	144.12532
EINECS:	608-832-1
Product Categories:
Mol File:	33135-50-1.mol

poly(L-lactide) Chemical Properties

Melting point	153 °C
density	1.27 g/cm3
storage temp.	2-8°C
optical activity	[α]22/D -153°, c = 0.5% in chloroform
InChIKey	BHIWKHZACMWKOJ-UHFFFAOYSA-N

Safety Information

Safety Statements	22-24/25
WGK Germany	3
HS Code	29181990

MSDS Information

Provider	Language
SigmaAldrich	English

poly(L-lactide) Usage And Synthesis

Physical properties	Poly(L-lactide) is a polymorphic material which has three forms of crystalline structure: α, β and γ. Poly(L-lactide) was found that a polymorphic material with a different form of crystalline structure exhibits different physical properties. Poly(L-lactide) has a low crystallization rate, compared to other thermoplastics, and it is rather easy to define the processing conditions to obtain Poly(L-lactide) products with a wide range of degree of crystallinity.
Uses	Poly(L-lactide) is a biodegradable polymer for medical device and pharmaceutical applications. It is used to fabricate resorbable medical devices that degrade over months in physiological conditions. Due to their history, polylactides are one of the easiest and most affordable biodegradable polymers for medical devices.
Chemical Properties	White powder
Uses	Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
Uses	medical device
Uses	PLLA can be used as a resorbable implant material for potential usage in biomedical applications. It can also be used in the formation of composite ceramic material for biological applications.
General Description	Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.

poly(L-lactide) Preparation Products And Raw materials

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