4-Aminophthalhydrazide

4-Aminophthalhydrazide
  • CAS No.:3682-14-2
Other grades of this product :
4-Aminophthalhydrazide Basic information
Uses
Product Name:4-Aminophthalhydrazide
Synonyms:ISOLUMINOL;6-amino-2,3-dihydrophthalazine-1,4-dione hydrate;6-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE;6-AMINO-2,3-DIHYDROPHTHALAZINE-1,4-DIONE;4-AMINOPHTHALHYDRAZIDE HYDRATE, 98%;4-AMINOPHTHALHYDRAZIDE MONOHYDRATE;6-AMINO-2-3-DIHYDRO-1-4-PHTHALAZINEDIONE CRYSTALLI;6-Amino-2,3-dihydro-1,4-phthal-
CAS:3682-14-2
MF:C8H7N3O2
MW:177.16
EINECS:
Product Categories:Luminols (Chemiluminescence);Analytical Chemistry;Chemiluminescence
Mol File:3682-14-2.mol
4-Aminophthalhydrazide Chemical Properties
Melting point 300 °C (lit.)
density 1.433±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in ammonium hydroxide, sodium carbonate or other base.
pka10.78±0.20(Predicted)
form Solid
color White to Off-White
Sensitive Air Sensitive
BRN 164804
InChIKeyHUDPLKWXRLNSPC-UHFFFAOYSA-N
CAS DataBase Reference3682-14-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
10-23
HS Code 29280000
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Aminophthalhydrazide Usage And Synthesis
Uses4-Aminophthalhydrazide is a chemiluminescent compound.
Chemical PropertiesPowder
Uses4-Aminophthalhydrazide has been used in:
  • chemiluminescence-based reactive oxygen species (ROS) assay in bone marrow (BM) neutrophils post-Yersinia pseudotuberculosis infection
  • neutrophil ROS assays post-K. pneumonia exposure
  • neutrophil ROS assays in response to formylated-methionine-leucine-proline
Biochem/physiol Actions4-Aminophthalhydrazide or isoluminol is a chemiluminescent compound that comprises a phthalazine ring. It is more hydrophilic than luminol. Isoluminol is commercially used in a wide variety of in vitro immunoassays and is a chemiluminescence amplifier for studying reactive oxygen species. It is also useful as an electroluminescence (ECL) biosensor and as a probe for rapid microbial detection.

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