1-Methyl-L-histidine

1-Methyl-L-histidine
  • CAS No.:332-80-9
Other grades of this product :
1-Methyl-L-histidine Basic information
Product Name:1-Methyl-L-histidine
Synonyms:METHYLHISTIDINE, L-1-;METHYLHISTIDINE, L-3-;1-METHYL-L-HISTIDINE;1-METHYLHISTIDINE;3-(1-METHYLIMIDAZOL-4-YL)-L-ALANINE;3-(1-METHYLIMIDAZOL-5-YL)-L-ALANINE;1-Methyl-L-histidine >=98.0% (TLC);1-N-Methyl-L-histidine
CAS:332-80-9
MF:C7H11N3O2
MW:169.18
EINECS:206-368-0
Product Categories:Pharmaceutical Raw Materials;Histidine [His, H];Amino Acids and Derivatives;Amino acids methyl、ethyl、t-butyl series;Amino Acids & Derivatives;Heterocycles;Inhibitors
Mol File:332-80-9.mol
1-Methyl-L-histidine Chemical Properties
Melting point ~240 °C (dec.) (lit.)
alpha -24 º (c=2% in H2O)
Boiling point 298.47°C (rough estimate)
density 1.2509 (rough estimate)
refractive index 1.5950 (estimate)
storage temp. 2-8°C(protect from light)
solubility Methanol (Slightly), Water (Slightly, Sonicated)
form Solid
pka1.69(at 25℃)
color Off-White to Pale Beige
optical activity[α]20/D 24±1°, c = 2% in H2O
BRN 9727
Stability:Hygroscopic
CAS DataBase Reference332-80-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25-22
WGK Germany 3
HS Code 29332900
MSDS Information
ProviderLanguage
SigmaAldrich English
1-Methyl-L-histidine Usage And Synthesis
Chemical PropertiesBeige powder
UsesThe urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent developm ent of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
UsesThe urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
1-Methyl-L-histidine Preparation Products And Raw materials

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