3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid

3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid
  • CAS No.:162401-62-9
Other grades of this product :
3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Basic information
Product Name:3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid
Synonyms:3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid;3-CyclopropyMethoxy-4-difluoroMethoxy benzoic acid;Benzoic acid, 3-(cyclopropylMethoxy)-4-(difluoroMethoxy)-;CYCLOPROPYL DIFLUOROMETHOXYBENOZOIC ACID;3-CyclopropylMethoxy-4-isopropoxy-benzoic acid;RofluMilast InterMediate II;Roflumilast intermediate (3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid);Roflumilast Acid Impurity
CAS:162401-62-9
MF:C12H12F2O4
MW:258.22
EINECS:605-288-7
Product Categories:Roflumilast interemdiate;Intermediates
Mol File:162401-62-9.mol
3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Chemical Properties
Melting point 118-120℃
Boiling point 356.4±37.0 °C(Predicted)
density 1.355±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka3.87±0.10(Predicted)
form Solid
color White to Off-White
InChIKeyIGFDIFLMMLWKKY-UHFFFAOYSA-N
CAS DataBase Reference162401-62-9
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR 2811
HazardClass 6.1
PackingGroup 
HS Code 2918999090
MSDS Information
3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Usage And Synthesis
UsesAn impurity and intermediate in the preparation of selective phosphodiesterase 4 (PDE4) inhibitor, Roflumilast (R639700).
3-Cyclopropylmethoxy-4-difluoromethoxy-benzoic acid Preparation Products And Raw materials

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