H2N-PEG4-tBu

H2N-PEG4-tBu
  • CAS No.:581065-95-4
Other grades of this product :
H2N-PEG4-tBu Basic information
Product Name:H2N-PEG4-tBu
Synonyms:H2N-PEG4-tBu;tert-Butyl 15-aMino-4,7,10,13-tetraoxapentadecanoate;2-[2-[2-[2-(2-tert-Butoxycarbonylethoxy)ethoxy]ethoxy]ethoxy]ethylamine;H2N-PEG4-CH2CH2COOtBu;Amino-dPEG4-t-butyl ester;tert-Butyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate;H2N-PEG4-CH2CH2COOtBu;Amino-PEG4-t-butyl ester
CAS:581065-95-4
MF:C15H31NO6
MW:321.41
EINECS:
Product Categories:PEG-COOtBu;peg
Mol File:581065-95-4.mol
H2N-PEG4-tBu Chemical Properties
Boiling point 400.1±35.0 °C(Predicted)
density 1.040±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in Water, DMSO, DCM, DMF
form clear liquid
pka8.74±0.10(Predicted)
color Colorless to Light yellow
CAS DataBase Reference581065-95-4
Safety Information
HS Code 2922190090
MSDS Information
H2N-PEG4-tBu Usage And Synthesis
DescriptionAmino-PEG4-t-butyl ester is a PEG reagent containing an amino (NH2) and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl (Boc) can be deprotected under acidic conditions.
Usesis a linker-cytotoxin conjugate. Linker-cytotoxin conjugate is related to antibody-cytotoxin and antibody-drug conjugates and related compounds.

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