Product

Methyl 4-hydroxyphenylacetate

CAS No.：14199-15-6

Other grades of this product :

Methyl 4-hydroxyphenylacetate Basic information

Product Name:	Methyl 4-hydroxyphenylacetate
Synonyms:	METHYL 4-HYDROXYPHENYLACETATE;METHYL P-HYDROXYPHENYL ACETATE;4-HYDROXYPHENYLACETIC ACID METHYL ESTER;4-hydroxy-benzeneaceticacimethylester;Acetic acid, (p-hydroxyphenyl)-, methyl ester;p-Hydroxyphenylacetic acid methyl ester;Methyl 4-hydroxyphenylacetate 99%;Methyl 4-hydroxyphenylacetate, 98+%
CAS:	14199-15-6
MF:	C9H10O3
MW:	166.17
EINECS:	238-050-2
Product Categories:	C8 to C9;Carbonyl Compounds;Aromatic Esters;Esters;Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;pharmaceutical
Mol File:	14199-15-6.mol

Methyl 4-hydroxyphenylacetate Chemical Properties

Melting point	55-58 °C (lit.)
Boiling point	162-163 °C/5 mmHg (lit.)
density	1.1708 (rough estimate)
refractive index	1.5500 (estimate)
Fp	163°C/5mm
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform, Methanol
pka	9.72±0.13(Predicted)
form	Crystals
color	White to pale yellow
BRN	2087538
InChIKey	XGDZEDRBLVIUMX-UHFFFAOYSA-N
LogP	1.6
CAS DataBase Reference	14199-15-6(CAS DataBase Reference)
NIST Chemistry Reference	Benzeneacetic acid, 4-hydroxy-, methyl ester(14199-15-6)
EPA Substance Registry System	Benzeneacetic acid, 4-hydroxy-, methyl ester (14199-15-6)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
TSCA	Yes
HS Code	29182990

MSDS Information

Provider	Language
4-Hydroxyphenylacetic acid methyl ester	English
SigmaAldrich	English
ACROS	English
ALFA	English

Methyl 4-hydroxyphenylacetate Usage And Synthesis

Chemical Properties	WHITE TO PALE YELLOW CRYSTALS
Uses	Methyl 4-hydroxyphenylacetate was used in the synthesis of 4-(2-hydroxy-3-isopropylamino)propoxyphenylacetic acid.
Definition	ChEBI: A methyl ester resulting from the formal condensation of the carboxy group of 4-hydroxyphenylacetic acid with methanol. It has been isolated from Penicillium chrysogenum.
General Description	Methyl 4-hydroxyphenylacetate inhibits the activity of tobacco mosaic virus (TMV).

Methyl 4-hydroxyphenylacetate Preparation Products And Raw materials

Raw materials	Methanol-->4-Hydroxyphenylacetic acid-->Benzeneacetic acid, 4-(methoxymethoxy)-, methyl ester-->methyl 2-(4-(allyloxy)phenyl)acetate-->4-tert-ButyldiMethylsilyloxybenzeneacetic Acid Methyl Ester-->2-CHLORO-4'-HYDROXYACETOPHENONE-->jacaranone-->4'-Hydroxyacetophenone-->4-Hydroxyphenethyl alcohol
Preparation Products	2-[3-(2H-Benzotriazol-2-yl)-4-hydroxyphenyl]ethyl methacrylate-->Olopatadine-->4-[[(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenol-->armepavine-->(4-METHOXYCARBONYLMETHYLPHENYL)BORONIC ACID-->METHYL 4-METHOXYPHENYLACETATE-->4-PHENOXYPHENYLACETIC ACID

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