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| Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate Basic information |
| Product Name: | Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate | | Synonyms: | abt199 int 2;methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate;ABT199 intermediate 3;ABT199 intermediates;Methyl 2-((1H-pyrrolo[2,3-b]pyrin-
5-yl)oxy)-4-fluorobenzoate;ABT-199 Intermediate;methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate;Methyl-2-((1H-pyrrolo[2,3-b]pyridine-5-yl)oxy)-4-fluorobenzoate | | CAS: | 1235865-75-4 | | MF: | C15H11FN2O3 | | MW: | 286.26 | | EINECS: | | Product Categories: | | Mol File: | 1235865-75-4.mol |
| Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate Chemical Properties |
| density | 1.377±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 13.21±0.40(Predicted) | | CAS DataBase Reference | 1235865-75-4 |
| Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate Usage And Synthesis |
| Uses | Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate is the intermediate for ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
| Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate Preparation Products And Raw materials |
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![Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate](/img/1235865-75-4.jpg "Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate")
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