2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL

CAS No.：5197-62-6

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2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Basic information

Product Name:	2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
Synonyms:	8-Chloro-3,6-dioxaoctane-1-ol;Diethylene glycol mono(2-chloroethyl) ether;2-[2-(2-Chloroethoxy)ethoxy]ethanol,95%;8-Chloro-3,6-dioxa-1-octanol;8-Chloro-3,6-dioxaoctanol;NSC 2636;2-[2-(2-Chloroethoxy)ethoxy]ethanol 96%;2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL
CAS:	5197-62-6
MF:	C6H13ClO3
MW:	168.62
EINECS:	225-984-0
Product Categories:	Aliphatics;Intermediates;Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols;Polyethyleneglycol Derivatives
Mol File:	5197-62-6.mol

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Chemical Properties

Boiling point	117-120 °C5 mm Hg(lit.)
density	1.16 g/mL at 25 °C(lit.)
refractive index	n20/D 1.458(lit.)
Fp	225 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly)
pka	14.36±0.10(Predicted)
form	Liquid
color	Clear slightly yellow
BRN	1739194
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey	KECMLGZOQMJIBM-UHFFFAOYSA-N
CAS DataBase Reference	5197-62-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
HS Code	29094990

MSDS Information

Provider	Language
SigmaAldrich	English

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Usage And Synthesis

Chemical Properties	colourless liquid
Uses	2-[2-(2-Chloroethoxy)ethoxy]ethanol is used in the preparation of ethylene glycol based amino acids. 2-[2-(2-Chloroethoxy)ethoxy]ethanol is also used in the preparation of polymers for direct and amplified DNA detection.
Uses	2-[2-(2-Chloroethoxy)ethoxy]ethanol was used in the synthesis of 1-[3-(2-aminoethyl)-1H-indol-5-yloxy]-3,6-dioxa-8-mercaptooctane. It was also used in the synthesis of modified oligonucleotides bearing a disulfide or a thiol function at the 3′-end and other modifications at the 5′-end.

2-[2-(2-CHLOROETHOXY)ETHOXY]ETHANOL Preparation Products And Raw materials

Raw materials	2-Chloroethanol-->2-(2-Chloroethoxy)ethanol-->Triethylene glycol-->ETHYLENE OXIDE-->Ethylene glycol
Preparation Products	2-[2-[2-(2-chloroethoxy)ethoxy]ethoxy]ethanol-->1,4-Dioxane-->2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL-->t-Boc-N-Amido-PEG3-propargyl-->Acetic acid, [2-[2-(2-aminoethoxy)ethoxy]ethoxy]--->1,4,7,10,13-PENTAOXA-16-AZACYCLOOCTADECANE-->2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL-->1,2-Bis(2-chloroethoxy)ethane

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