(-)-Corey lactone 4-phenylbenzoate alcohol

(-)-Corey lactone 4-phenylbenzoate alcohol
  • CAS No.:31752-99-5
Other grades of this product :
(-)-Corey lactone 4-phenylbenzoate alcohol Basic information
Description
Product Name:(-)-Corey lactone 4-phenylbenzoate alcohol
Synonyms:(3AALPHA,4ALPHA,5BETA,6AALPHA)-(-)-HEXAHYDRO-4-(HYDROXYMETHYL)-2-OXO-2H-CYCLOPENTA[B]FURAN-5-YL 1,1'-BIPHENYL-4-CARBOXYLATE;(-)-COREY LACTONE 4-PHENYLBENZOATE;4-Phenylbenzoyl corey lactone;(-)-COREY LACTONE 4-PHENYLBENZOATE ALCOHOL 99%;(-)-COREY LACTONE, 4-PHENYLBENZOATE ALCOHOL;(3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzoyloxy)cyclopenta[b]furan-2-one, 99%;[1,1'-Biphenyl]-4-carboxylicacid,(3aR,4S,5R,6aS)-hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-ylester;BPCOD
CAS:31752-99-5
MF:C21H20O5
MW:352.38
EINECS:608-667-5
Product Categories:Prostaglandins;Latanoprost;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:31752-99-5.mol
(-)-Corey lactone 4-phenylbenzoate alcohol Chemical Properties
Melting point 131-132 °C(lit.)
Boiling point 446°C (rough estimate)
alpha -89 º (c=1, CHCl3)
density 1.1818 (rough estimate)
refractive index 1.5400 (estimate)
storage temp. 2-8°C
solubility Chloroform, Ethyl Acetate
form Solid
pka14.79±0.10(Predicted)
color Off-White to Pale Yellow
optical activity[α]20/D 87°, c = 1 in chloroform
Water Solubility insoluble
BRN 1294692
InChIKeySZJVIFMPKWMGSX-UHFFFAOYSA-N
CAS DataBase Reference31752-99-5(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
HS Code 29322090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
(-)-Corey lactone 4-phenylbenzoate alcohol Usage And Synthesis
Description(-)-Corey lactone 4-phenylbenzoate alcohol is one of the isomers of biphenyl-4-formylcorilactone, which can be used for the synthesis of prostaglandins. Prostaglandins are a class of important endogenous physiologically active substances, important mediators of various physiological processes, and have high pharmacological activity. Clinically, prostaglandins are all artificially synthesized.
Chemical PropertiesOff-White to Pale Yellow Solid
Uses(-) Corey lactone phenylbenzoate is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF.

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