Ethyl (3S)-piperidine-3-carboxylate

CAS No.：37675-18-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Ethyl (3S)-piperidine-3-carboxylate Basic information

Product Name:	Ethyl (3S)-piperidine-3-carboxylate
Synonyms:	(S)-(+)-ETHYL NIPECOTATE;(S)-ETHYL-NIPECOTATE;3-Piperidinecarboxylicacid, ethyl ester, (S)-;(3s)-(+)-ethyl Nipecotate;(S)-ETHYL PIPERIDINE-3-CARBOXYLATE;(S)-(+)-NIPECOTIC ACID ETHYL ESTER;(S)-NIPECOTIC ACID ETHYL ESTER;(S)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS:	37675-18-6
MF:	C8H15NO2
MW:	157.21
EINECS:	609-464-4
Product Categories:	Piperidine;Heterocyclic Compounds;Nitrogen cyclic compounds;Chiral Building Blocks;Esters (Chiral);Synthetic Organic Chemistry
Mol File:	37675-18-6.mol

Ethyl (3S)-piperidine-3-carboxylate Chemical Properties

Boiling point	102-104 °C/7 mmHg(lit.)
density	1.043 g/mL at 25 °C
refractive index	n20/D 1.471
Fp	77 °C
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka	9.35±0.10(Predicted)
form	clear liquid
color	Colorless to Almost colorless
Specific Gravity	1.012
Sensitive	Light, Air & Moisture Sensitive
CAS DataBase Reference	37675-18-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38-41
Safety Statements	26-36/37/39-39-36
RIDADR	NA 1993 / PGIII
WGK Germany	3
HS Code	29339900

MSDS Information

Ethyl (3S)-piperidine-3-carboxylate Usage And Synthesis

Chemical Properties	Colorless liquid
Uses	Reactant for synthesis of: DPP-4 inhibitors JAK2 inhibitors Serotonin and noradrenaline reuptake inhibitors Human tryptase inhibitors Anti-thrombotic nicecotamides Reactive for oxidative C-arylation of free (NH)-heterocycles via direct (sp3) C-H bond functionalization

Ethyl (3S)-piperidine-3-carboxylate Preparation Products And Raw materials

Preparation Products

Ethyl (3R)-piperidine-3-carboxylate-->3(R)-PIPERIDINEMETHANOL-->(R)-N-Boc-3-aminomethylpiperidine

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