Ethyl (3S)-piperidine-3-carboxylate

Ethyl (3S)-piperidine-3-carboxylate
  • CAS No.:37675-18-6
Other grades of this product :
Ethyl (3S)-piperidine-3-carboxylate Basic information
Product Name:Ethyl (3S)-piperidine-3-carboxylate
Synonyms:(S)-(+)-ETHYL NIPECOTATE;(S)-ETHYL-NIPECOTATE;3-Piperidinecarboxylicacid, ethyl ester, (S)-;(3s)-(+)-ethyl Nipecotate;(S)-ETHYL PIPERIDINE-3-CARBOXYLATE;(S)-(+)-NIPECOTIC ACID ETHYL ESTER;(S)-NIPECOTIC ACID ETHYL ESTER;(S)-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS:37675-18-6
MF:C8H15NO2
MW:157.21
EINECS:609-464-4
Product Categories:Piperidine;Heterocyclic Compounds;Nitrogen cyclic compounds;Chiral Building Blocks;Esters (Chiral);Synthetic Organic Chemistry
Mol File:37675-18-6.mol
Ethyl (3S)-piperidine-3-carboxylate Chemical Properties
Boiling point 102-104 °C/7 mmHg(lit.)
density 1.043 g/mL at 25 °C
refractive index n20/D 1.471
Fp 77 °C
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka9.35±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
Specific Gravity1.012
Sensitive Light, Air & Moisture Sensitive
CAS DataBase Reference37675-18-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38-41
Safety Statements 26-36/37/39-39-36
RIDADR NA 1993 / PGIII
WGK Germany 3
HS Code 29339900
MSDS Information
Ethyl (3S)-piperidine-3-carboxylate Usage And Synthesis
Chemical PropertiesColorless liquid
UsesReactant for synthesis of:
  • DPP-4 inhibitors
  • JAK2 inhibitors
  • Serotonin and noradrenaline reuptake inhibitors
  • Human tryptase inhibitors
  • Anti-thrombotic nicecotamides
Reactive for oxidative C-arylation of free (NH)-heterocycles via direct (sp3) C-H bond functionalization
Ethyl (3S)-piperidine-3-carboxylate Preparation Products And Raw materials
Preparation ProductsEthyl (3R)-piperidine-3-carboxylate-->3(R)-PIPERIDINEMETHANOL-->(R)-N-Boc-3-aminomethylpiperidine

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