N-PHTHALOYL-L-GLUTAMIC ACID

CAS No.：340-90-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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N-PHTHALOYL-L-GLUTAMIC ACID Basic information

Product Name:	N-PHTHALOYL-L-GLUTAMIC ACID
Synonyms:	(2S)-2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)pentanedioic acid;n-phthalyl-l-glutamicacid;N-PHTHALIMIDE L-GLUTAMINC ACID;N-PHTHALOYL-L-GLUTAMIC ACID;PHTHALYL-L-GLUTAMIC ACID;PHTHALOYL-L-GLUTAMIC ACID;PHT-GLU-OH;PHGA
CAS:	340-90-9
MF:	C13H11NO6
MW:	277.23
EINECS:	608-945-6
Product Categories:
Mol File:	340-90-9.mol

N-PHTHALOYL-L-GLUTAMIC ACID Chemical Properties

Melting point	160-162 °C(lit.)
alpha	-45°(20/D, c=1, C2H5OH)
Boiling point	519.0±40.0 °C(Predicted)
density	1.566±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	3.45±0.10(Predicted)
form	Powder
optical activity	[α]20/D 45°, c = 1 in ethanol
BRN	90136
LogP	-4.2-0.9 at 20℃ and pH1-7
Surface tension	72.4mN/m at 1g/L and 20℃
CAS DataBase Reference	340-90-9(CAS DataBase Reference)

Safety Information

Safety Statements	22-24/25
WGK Germany	3
RTECS	MA3820000

MSDS Information

Provider	Language
SigmaAldrich	English

N-PHTHALOYL-L-GLUTAMIC ACID Usage And Synthesis

Chemical Properties	white crystalline powder
Definition	ChEBI: A glutamic acid derivative that is L-glutamic acid in which the two hydrogens on the amino group are substituted by a phthaloyl group.

N-PHTHALOYL-L-GLUTAMIC ACID Preparation Products And Raw materials

Preparation Products

(R)-(+)-THALIDOMIDE-->PHTHALOYL-L-GLUTAMIC ANHYDRIDE-->4-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)BUTANOIC ACID

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