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| Product Name: | 4-Pyridyl acetone | | Synonyms: | 1-(4-Pyridyl)-2-propanone;4-Pyridinolacetone;(4-Pyridyl)acetone,98%;1-(4-Pyridinyl)-2-propanone CAS:;(4-PYRIDINEYL)-ACETONE;1-(4-Pyridyl)-2-acetone;Einecs 228-605-7;1-pyridin-4-ylacetone | | CAS: | 6304-16-1 | | MF: | C8H9NO | | MW: | 135.16 | | EINECS: | 228-605-7 | | Product Categories: | Pyridines | | Mol File: | 6304-16-1.mol |
| 4-Pyridyl acetone Chemical Properties |
| Melting point | 13°C | | Boiling point | 143°C 20mm | | density | 1.046±0.06 g/cm3(Predicted) | | refractive index | 1.5225 | | Fp | 143°C/20mm | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | pka | 4.90±0.10(Predicted) | | form | Oil | | color | Light Brown to Brown | | Water Solubility | Slightly soluble in water. | | BRN | 110960 | | InChIKey | ILRVKOYYFFNXDB-UHFFFAOYSA-N | | CAS DataBase Reference | 6304-16-1(CAS DataBase Reference) |
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ALFA
| English |
| 4-Pyridyl acetone Usage And Synthesis |
| Description | 1-(4-pyridyl)acetone is a yellow liquid, which is a key intermediate for synthesizing cardiac drug Milrinone. | | Preparation | 4-Pyridyl acetone can be prepared by reacting with 4-picoline and phenyllithium and ethyl acetate. | | Physical properties | 4-pyridyl acetone is a Light yellow to yellow liquid. | | Uses | (4-Pyridyl)acetone is a reactant in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic. | | Synthesis Reference(s) | Tetrahedron Letters, 25, p. 3297, 1984 DOI: 10.1016/S0040-4039(01)81368-X |
| 4-Pyridyl acetone Preparation Products And Raw materials |
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