3,4',5-TRIMETHOXY-TRANS-STILBENE

3,4',5-TRIMETHOXY-TRANS-STILBENE
  • CAS No.:22255-22-7
Other grades of this product :
3,4',5-TRIMETHOXY-TRANS-STILBENE Basic information
Product Name:3,4',5-TRIMETHOXY-TRANS-STILBENE
Synonyms:3,4',5-TRIMETHOXY-TRANS-STILBENE;(E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene;(E)-3,4',5-Trimethoxystilbene;3,5,4'-Trimethoxy-trans-stilbene;Trimethoxystilbene;3,4,5-TRIMETHOXY-TRANS-STILBENE 95+%;TRANS-1-(3,5-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHYLENE;TRISMETHOXY RESVERATROL
CAS:22255-22-7
MF:C17H18O3
MW:270.32
EINECS:694-659-7
Product Categories:Resveratrol;Intermediates & Fine Chemicals;Stilbenes;Pharmaceuticals
Mol File:22255-22-7.mol
3,4',5-TRIMETHOXY-TRANS-STILBENE Chemical Properties
Melting point 57°C
Boiling point 423.8±35.0 °C(Predicted)
density 1.104±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO: ≥34mg/mL
form powder to crystal
color white to tan
CAS DataBase Reference22255-22-7
Safety Information
Hazard Codes Xi,N
Risk Statements 36/37/38-50/53-41-37/38
Safety Statements 26-36/37/39-61-60-39
RIDADR UN 3077 9 / PGIII
MSDS Information
3,4',5-TRIMETHOXY-TRANS-STILBENE Usage And Synthesis
Descriptiontrans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM.
Chemical PropertiesPale Yellow Oil
UsesA resveratrol analog with a variety of pharmacology action, including anti-cancer properties, anti-allergic activity, estrogenic activity, antiangiogenic activity, and vascular-targeting activity against microtubule-destabilization
UsesA resveratrol analog with a variety of pharmacology action, including inst microtubule-destabilization
UsesPhenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced.
3,4',5-TRIMETHOXY-TRANS-STILBENE Preparation Products And Raw materials

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