4-Iodopyrazole

4-Iodopyrazole
  • CAS No.:3469-69-0
Other grades of this product :
4-Iodopyrazole Basic information
Product Name:4-Iodopyrazole
Synonyms:4-IODOPYRAZOLE;4-IODO-1H-PYRAZOLE;1H-PYRAZOLE, 4-IODO-;4-Iodo-1H-pyrazole 99%;Crizotinib Impurity 14;4-IODOPYRAZOLE 99%;4-Iodopyrazole ,98%;4-Lodophrazole
CAS:3469-69-0
MF:C3H3IN2
MW:193.97
EINECS:222-434-1
Product Categories:Halides;Pyrazoles & Triazoles;Pyrazoles & Triazoles;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Azoles;blocks;Iodides;Pyrazoles;PyrazolesHeterocyclic Building Blocks
Mol File:3469-69-0.mol
4-Iodopyrazole Chemical Properties
Melting point 108-110 °C (lit.)
Boiling point 291.9±13.0 °C(Predicted)
density 2.335±0.06 g/cm3(Predicted)
RTECS UQ7145000
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka12.99±0.50(Predicted)
form Crystalline Powder
color White to off-white
Water Solubility Soluble in water.
Sensitive Light Sensitive
InChIKeyLLNQWPTUJJYTTE-UHFFFAOYSA-N
CAS DataBase Reference3469-69-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
HazardClass IRRITANT
HS Code 29331990
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Iodopyrazole Usage And Synthesis
Chemical PropertiesWhite or off-white solid
Uses4-Iodopyrazole is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.
Uses4-Iodopyrazole was used in an indium-mediated synthesis of heterobiaryls.
General Description4-Iodopyrazole is a valuable intermediate for the synthesis of biologically active compounds. It undergoes iodination in the presence of iodine and ammonium hydroxide to yield 3,4-di-iodo- and 3,4,5-tri-iodo-pyrazole.
4-Iodopyrazole Preparation Products And Raw materials
Raw materials3,4-Diiodopyrazole-->4-Bromopyrazole-->Pyrazole-->1H-PYRAZOL-4-YLAMINE
Preparation Products4-Iodo-1-methyl-1H-pyrazole-->1-BENZYL-1H-PYRAZOLE-->1-Benzyl-4-iodo-1H-pyrazole

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