4-Iodopyrazole

4-Iodopyrazole
  • CAS No.:3469-69-0

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
4-Iodopyrazole Basic information
Product Name:4-Iodopyrazole
Synonyms:4-IODOPYRAZOLE;4-IODO-1H-PYRAZOLE;1H-PYRAZOLE, 4-IODO-;4-Iodo-1H-pyrazole 99%;Crizotinib Impurity 14;4-IODOPYRAZOLE 99%;4-Iodopyrazole ,98%;4-Lodophrazole
CAS:3469-69-0
MF:C3H3IN2
MW:193.97
EINECS:222-434-1
Product Categories:Halides;Pyrazoles & Triazoles;Pyrazoles & Triazoles;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Azoles;blocks;Iodides;Pyrazoles;PyrazolesHeterocyclic Building Blocks
Mol File:3469-69-0.mol
4-Iodopyrazole Chemical Properties
Melting point 108-110 °C (lit.)
Boiling point 291.9±13.0 °C(Predicted)
density 2.335±0.06 g/cm3(Predicted)
RTECS UQ7145000
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka12.99±0.50(Predicted)
form Crystalline Powder
color White to off-white
Water Solubility Soluble in water.
Sensitive Light Sensitive
InChIKeyLLNQWPTUJJYTTE-UHFFFAOYSA-N
CAS DataBase Reference3469-69-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
HazardClass IRRITANT
HS Code 29331990
MSDS Information
ProviderLanguage
SigmaAldrich English
4-Iodopyrazole Usage And Synthesis
Chemical PropertiesWhite or off-white solid
Uses4-Iodopyrazole is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.
Uses4-Iodopyrazole was used in an indium-mediated synthesis of heterobiaryls.
General Description4-Iodopyrazole is a valuable intermediate for the synthesis of biologically active compounds. It undergoes iodination in the presence of iodine and ammonium hydroxide to yield 3,4-di-iodo- and 3,4,5-tri-iodo-pyrazole.
4-Iodopyrazole Preparation Products And Raw materials
Raw materials3,4-Diiodopyrazole-->4-Bromopyrazole-->Pyrazole-->1H-PYRAZOL-4-YLAMINE
Preparation Products4-Iodo-1-methyl-1H-pyrazole-->1-BENZYL-1H-PYRAZOLE-->1-Benzyl-4-iodo-1H-pyrazole

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