Isosorbide dimethyl ether

Isosorbide dimethyl ether
  • CAS No.:5306-85-4
Other grades of this product :
Isosorbide dimethyl ether Basic information
Product Name:Isosorbide dimethyl ether
Synonyms:ISOSORBIDE DIMETHYL ETHER;DIMETHYL ISOBORBIDE;DIMETHYL ISOSORBIDE;2,5-DI-O-METHYL-1,4:3,6-DIANHYDRO-D-GLUCITOL;1,4:3,6-DIANHYDRO-2,5-DI-O-METHYL-D-GLUCITOL;1,4:3,6-DIANHYDRO-2,5-O-DIMETHYL-D-GLUCITOL;1,4:3,6-DIANHYDROSORBITOL 2,5-DIMETHYL ETHER;-3,6-Dimethoxyhexahydrofuro[3,2-b]furan
CAS:5306-85-4
MF:C8H14O4
MW:174.2
EINECS:226-159-8
Product Categories:Cosmetic;5306-85-4
Mol File:5306-85-4.mol
Isosorbide dimethyl ether Chemical Properties
Melting point -70°C
Boiling point 93-95 °C0.1 mm Hg(lit.)
density 1.15 g/mL at 25 °C(lit.)
vapor pressure 12.54Pa at 20℃
refractive index n20/D 1.461(lit.)
Fp 227 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
color Clear colorless to light yellow
PH7.0-8.0 (100g/l, H2O, 20℃)
optical activity[α]21/D +96.1°, c = 2 in chloroform
Water Solubility Soluble in water.
BRN 80854
InChIKeyMEJYDZQQVZJMPP-ULAWRXDQSA-N
LogP-1.62
CAS DataBase Reference5306-85-4(CAS DataBase Reference)
Safety Information
Safety Statements 23-24/25
WGK Germany 3
HS Code 29092000
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
Isosorbide dimethyl ether Usage And Synthesis
Chemical Propertiesclear colorless to light yellow liquid. very stable under neutral conditions, hygroscopic and miscible with most organic solvents.
Usesdimethyl isosorbide is a carrier, solvent, and viscosity controller. Its particular skin-penetrating ability opens the possibility of enhancing active substance efficacy in optical products. Its physical characteristics and solubility properties are superior to those of propylene glycol, glycerin, or ethyl alcohol.
UsesIsosorbide dimethyl ether (DMI), a sustainable solvent, is widely used in various cosmetic and pharmaceutical formulations.General applications:DMI can be used as an alternative green solvent for epoxidation of cyclooctene, Baylis–Hillman reaction of isomaltulose-derived aldehydes with α,β-unsaturated ketones and also in solid-phase synthesis.It can be used as a coalescent for water-borne paints, where it acts as a co-solvent during the water loss phase and as a coalescing agent during the film formation.
PreparationIsosorbide dimethyl ether is synthesized from isosorbide by methylation.Isosorbide dimethyl ether is obtained from stock like D-sorbitol, which is mainly derived from the hydrogenation of D-glucose.Isosorbide dimethyl has a low level of toxicity and is referred to as a green solvent due to its production from renewable/raw material.The boiling point of this solvent is high.lt is used as a substitute to dimethyl sulfoxide,and dimethylformamide-like solvents.
General DescriptionDimethyl isosorbide (DMI) is a biobased greener solvent and thus aligns with "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries".
Flammability and ExplosibilityNonflammable
Isosorbide dimethyl ether Preparation Products And Raw materials
Raw materialsIsosorbide-->Dimethyl sulfate-->Dimethyl carbonate-->Methanol-->Trimethyl phosphate-->Sorbitol-->Chloromethane
Preparation ProductsIsomannide

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