Flucloxacillin sodium

CAS No.：1847-24-1

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This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
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Flucloxacillin sodium Basic information

Product Name:	Flucloxacillin sodium
Synonyms:	(2s-(2-alpha,5-alpha,6-beta))-al;sodium [2S-(2alpha,5alpha,6beta)]-6-[[[3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-yl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;Flucloxacillin sodium BP98;3-dimethyl-7-oxo-henyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-monosodiums;4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(((3-(2-chloro-6-fluorop;5-methyl-3-(2-chloro-6-fluorophenyl)-4-isoxazolylpenicillinsodium;floxacillinsodium;floxapensodium
CAS:	1847-24-1
MF:	C19H18ClFN3NaO5S
MW:	477.87
EINECS:	217-428-0
Product Categories:	Isoquinolines ,Quinolines ,Quinaldines;Peptide Synthesis/Antibiotics;API;APIs;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:	1847-24-1.mol

Flucloxacillin sodium Chemical Properties

Melting point	176-178°C
Boiling point	677℃
RTECS	XH8680000
Fp	>110°(230°F)
storage temp.	2-8°C
solubility	H2O: soluble20mg/mL, clear
form	powder
color	white to beige
Water Solubility	Soluble in water
Sensitive	Light Sensitive
InChIKey	OTEANHMVDHZOPB-SLINCCQESA-M
CAS DataBase Reference	1847-24-1(CAS DataBase Reference)

Safety Information

WGK Germany	3
Toxicity	LD50 oral in rabbit: > 8gm/kg

MSDS Information

Flucloxacillin sodium Usage And Synthesis

Chemical Properties	White Solid
Uses	Antibacterial;Peptidoglycan synthesis inhibitor
Uses	Flucloxacillin sodium has been used as a β-lactam antibiotic to study its effects on methicillin-resistant?Staphylococcus aureus?(MRSA) ΔfloA?mutant.
Uses	Flucloxacillin, a new semisynthetic penicillin
General Description	Flucloxacillin sodium, a sodium salt of flucloxacillin, is a member of the penicillin class.
Biochem/physiol Actions	Flucloxacillin exhibits antimicrobial property.

Flucloxacillin sodium Preparation Products And Raw materials

Raw materials

3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid-->2-Chloro-6-fluorobenzaldehyde-->6-Aminopenicillanic acid

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