4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER

CAS No.：6975-44-6

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4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER Basic information

Product Name:	4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER
Synonyms:	4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER;2,4-Dihydroxy-5-(ethoxycar;4,6-DIHYDROXYPYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER;BUTTPARK 153\57-32;SPECS AC-907/34126052;Ethyl 4,6-dihydroxynicotinate;ethyl 6-hydroxy-4-oxo-1H-pyridine-3-carboxylate;6-hydroxy-4-keto-1H-pyridine-3-carboxylic acid ethyl ester
CAS:	6975-44-6
MF:	C8H9NO4
MW:	183.16
EINECS:
Product Categories:	Pyridine
Mol File:	6975-44-6.mol

4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER Chemical Properties

Melting point	214-217°
Boiling point	339.4±42.0 °C(Predicted)
density	1.380
storage temp.	Inert atmosphere,Room Temperature
form	powder to crystal
pka	4.50±1.00(Predicted)
color	White to Orange to Green
CAS DataBase Reference	6975-44-6

Safety Information

Risk Statements	36/37/38
Safety Statements	26-36/37/39
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER Usage And Synthesis

Chemical Properties	White solid
Uses	Ethyl 4,?6-?dihydroxynicotinate has been used as a reactant is the synthesis of pyridazinopyrimidinone and pyridopyrimidinone derivatives as PDE5 inhibitors and for the synthesis of pyridone diaryl ether non-nucleoside inhibitors of HIV-1 reverse transcriptase.

4, 6-DIHYDROXYNICOTINIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials	Hydrochloric acid-->Acetic anhydride-->Ammonium hydroxide-->Triethyl orthoformate-->Diethyl 1,3-acetonedicarboxylate
Preparation Products	4,6-DICHLORO-3-PYRIDINEMETHANOL-->6-Chloro-1H-pyrazolo[4,3-c]pyridine

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