PURPURIN

PURPURIN
  • CAS No.:81-54-9
Other grades of this product :
PURPURIN Basic information
Product Name:PURPURIN
Synonyms:CI NO 58205;CI 58205;1,2,4-TRIHYDROXY-9,10-ANTHRACENEDIONE;1,2,4-TRIHYDROXYANTHRAQUINONE;ALIZARIN PURPURIN;1,2,4-trihydroxyanthracene-9,10-dione;PURPURIN, FOR THE DETECTION OF B, PB;PURPURIN
CAS:81-54-9
MF:C14H8O5
MW:256.21
EINECS:201-359-8
Product Categories:Anthraquinones, Hydroquinones and Quinones;Anthraquinones;Intermediates of Dyes and Pigments;Hydroxyanthraquinones
Mol File:81-54-9.mol
PURPURIN Chemical Properties
Melting point 253-256 °C(lit.)
Boiling point 359.45°C (rough estimate)
density 1.659
refractive index 1.4825 (estimate)
Fp 113 °C
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
pka7.05±0.20(Predicted)
form Powder
Colour Index 58205
color Brown-red to brown
Water Solubility 6.405mg/L(25 ºC)
Merck 14,7945
BRN 1887127
CAS DataBase Reference81-54-9
EPA Substance Registry SystemPurpurin (81-54-9)
Safety Information
Hazard Codes Xi,C,F
Risk Statements 36/37/38-34-11
Safety Statements 26-36-45-36/37/39-16
WGK Germany 3
RTECS CB8200000
HS Code 29146990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
PURPURIN Usage And Synthesis
Chemical Propertiesbrown-red to brown powder
Usesxanthin oxidase inhibitor, irritant
UsesPurpurin is an anthraquinone derivative and is well known as a colour pigment derived from madder plants. Purpurin was extensively utilized in herbal remedies, in food colouring and dyes for cotton pr inting. Due to the high antioxidant activity exhibited by anthraquinone compounds, purpurin was determined through studies to possess potential radical scavenging effects. Purprin has also been shown to have inhibitory effects towards serine protease.
UsesA xanthine oxidase inhibitor.
UsesPurpurin is a naturally occurring reddish-yellow pigment found in madder root (R. tinctorum) that has been used both in herbal remedies and as food coloring. It can also by synthetically derived from 9,10-anthraquinone. Purpurin is protective against a number of food-derived heterocyclic amines in bacterial mutagenicity assays through its inhibition of CYP450-dependent N-hydroxylation and reduction of N-hydroxylamines. Purpurine can also inhibit (IC50 = 6.6 μM) spermidine-induced autoactivation of plasma hyaluronan-binding protein, a serine protease that can activate coagulation factor VII and prourokinase.
DefinitionChEBI: A trihydroxyanthraquinone derived from anthracene by substitution with oxo groups at C-9 and C-10 and with hydroxy groups at C-1, C-2 and C-4.
Purification MethodsCrystallise purpurin from aqueous EtOH, dry it at 100o. [Beilstein 8 IV 3568.]

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