2,4-Difluoronitrobenzene

2,4-Difluoronitrobenzene
  • CAS No.:446-35-5
Other grades of this product :
2,4-Difluoronitrobenzene Basic information
Synthesis
Product Name:2,4-Difluoronitrobenzene
Synonyms:1,3-difluoro-4-nitrobenzene;1-Nitro-2,4-difluorobenzene;2,4-difluoro-1-nitro-benzen;2,4-Difluronitrobenzene;Benzene, 2,4-difluoro-1-nitro-;2,4-DIFLUORO-1-NITROBENZENE;2,4-DIFLUORONITROBENZENE;2,4-DIFLUORO NITROBENZEN
CAS:446-35-5
MF:C6H3F2NO2
MW:159.09
EINECS:207-167-0
Product Categories:Fluorine series;alkyl Fluorine| nitro-compound;HALIDE;Aromatic Hydrocarbons (substituted) & Derivatives
Mol File:446-35-5.mol
2,4-Difluoronitrobenzene Chemical Properties
Melting point 9-10 °C (lit.)
Boiling point 203-204 °C (lit.)
density 1.451 g/mL at 25 °C (lit.)
vapor density >1 (vs air)
refractive index n20/D 1.511(lit.)
Fp 195 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Light yellow to Brown
Specific Gravity1.45
Water Solubility Insoluble in water.
BRN 2048034
Stability:Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
InChIKeyRJXOVESYJFXCGI-UHFFFAOYSA-N
CAS DataBase Reference446-35-5(CAS DataBase Reference)
NIST Chemistry Reference2,4-Difluoronitrobenzene(446-35-5)
EPA Substance Registry System2,4-Difluoronitrobenzene (446-35-5)
Safety Information
Hazard Codes T,Xi,Xn
Risk Statements 25-36/37/38-23/24/25-20/21/22
Safety Statements 26-45-36/37/39-23
RIDADR UN 2810 6.1/PG 1
WGK Germany 3
RTECS CZ5730000
Hazard Note Irritant
TSCA T
HazardClass 6.1
PackingGroup III
HS Code 29049090
MSDS Information
ProviderLanguage
2,4-Difluoronitrobenzene English
SigmaAldrich English
ACROS English
ALFA English
2,4-Difluoronitrobenzene Usage And Synthesis
SynthesisKF with n-Hexadecyltrimethylammonium bromide as the PTC has been shown recently to work in dimethylformamide (DMF), important owing to the low cost16 of DMF.
Chemical Propertiesyellow liquid
Uses2,4-Difluoronitrobenzene has been used in the synthesis of: 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction; (±)-horsfiline; resin-bound 2-arylaminobenzimidazoles.2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents.
Uses2,4-Difluoronitrobenzene has been used in the synthesis of 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction, (±)-horsfiline and resin-bound-2-arylaminobenzimidazoles.
Uses2,4-Difluoronitrobenzene has been used in the synthesis of:
  • 2,4-difluoro-5-nitrobenzenesulfonic acid via sulfonation reaction
  • (±)-horsfiline
  • resin-bound 2-arylaminobenzimidazoles
General DescriptionNucleophilic aromatic substitution of 2,4-difluoronitrobenzene with morpholine has been investigated using flow reactor with simulated moving bed (SMB) chromatography module.

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