N-Boc-L-Histidine

CAS No.：17791-52-5

Other grades of this product :

N-Boc-L-Histidine Basic information

Product Name:	N-Boc-L-Histidine
Synonyms:	Nalpha-Boc-L-histidine Boc-His-OH;N(ɑ)-Boc-L-histidine;BOC-HISTIDINE;BOC-HIS-OH;N(^a)-Boc-L-histidine, 98+%;(S)-2-((tert-butoxycarbonyl)aMino)-3-(1H-iMidazol-4-yl)propanoic acid;N^α-BOC-L-Histidine;Boc-His-OH 99%
CAS:	17791-52-5
MF:	C11H17N3O4
MW:	255.27
EINECS:	241-768-9
Product Categories:	Histidine [His, H];Boc-Amino Acids and Derivative;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Boc-Amino acid series;AMINOACIDS DERIVATIVES;Amino Acids
Mol File:	17791-52-5.mol

N-Boc-L-Histidine Chemical Properties

Melting point	195 °C (dec.)(lit.)
alpha	25.5 º (C=1, MEOH 25 ºC)
Boiling point	398.5°C (rough estimate)
density	1.2235 (rough estimate)
refractive index	26 ° (C=1, MeOH)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Sparingly, Heated)
form	Powder, Crystals and/or Chunks
pka	3.56±0.10(Predicted)
color	White to off-white
optical activity	[α]20/D +26°, c = 1 in methanol
BRN	755289
CAS DataBase Reference	17791-52-5(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

N-Boc-L-Histidine Usage And Synthesis

Chemical Properties	WHITE FINE POWDER
Uses	Nα-Boc-L-histidine is an N-Boc-protected form of L-Histidine (H456010). L-Histidine is an essential amino acid that plays an important role in mitochondrial glutamine transport and has potential of abolishing oxidative stress caused by brain edema.L-Histidine promotes zinc uptake in human erythrocyes and also has potential as an antioxidant therapy for acute mammary inflammation in cattle.

N-Boc-L-Histidine Preparation Products And Raw materials

Raw materials	L-Histidine hydrochloride monohydrate-->L-Histidine, N-(2,2,2-trifluoroacetyl)-, methyl ester-->2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile-->BOC-HIS(BZL)-OH-->N,N'-Di-tert-butoxycarbonyl-L-histidine-->BOC-HIS(BOM)-OH-->BOC-HIS(Z)-OH-->L-Histidine-->Di-tert-butyl dicarbonate-->L-Histidine hydrochloride
Preparation Products	tert-Butyl carbazate-->Boc-L-Histidine(Tosyl)

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