4-Morpholinoaniline

CAS No.：2524-67-6

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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4-Morpholinoaniline Basic information

Product Name:	4-Morpholinoaniline
Synonyms:	p-Morpholinoaniline, 98+%;4-(4-Morpholinyl)aniline;4-(4-Morpholinyl)aniline, 98+%;4-(4-morpholinyl)-benzenamin;4-(4-MORPHOLINO)ANILINE, 98+%;4-MORPHOLINOANILINE, 98+%;4-Morpholinoaniline or N-(4-Aminophenyl)morpholine;4-morpholin-4-ylaniline hydrochloride
CAS:	2524-67-6
MF:	C10H14N2O
MW:	178.23
EINECS:	219-760-1
Product Categories:	Building Blocks;Heterocyclic Building Blocks;Aromatic Morpholines;pharmacetical;Morpholines
Mol File:	2524-67-6.mol

4-Morpholinoaniline Chemical Properties

Melting point	132-135 °C(lit.)
Boiling point	310.47°C (rough estimate)
density	1.0777 (rough estimate)
refractive index	1.5250 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in chloroform, ethyl acetate.
form	Crystalline Powder
pka	6.72±0.40(Predicted)
color	Purple to brown
BRN	150957
InChIKey	PHNDZBFLOPIMSM-UHFFFAOYSA-N
CAS DataBase Reference	2524-67-6(CAS DataBase Reference)
EPA Substance Registry System	4-(4-Morpholino)aniline (2524-67-6)

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	36/37/38-20/21/22
Safety Statements	26-37/39-36/37/39-22
RIDADR	UN2811
WGK Germany	3
Hazard Note	Irritant
TSCA	Yes
HazardClass	6.1
HS Code	29349990

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English
ALFA	English

4-Morpholinoaniline Usage And Synthesis

Chemical Properties	PURPLE TO BROWN CRYSTALLINE POWDER
Uses	4-Morpholinoaniline is a morpholine derivative used in the preparation of central nervous system (CNS) active agents. 4-Morpholinoaniline is also one of the primary aromatic amines used in the colour developing process in photographs.
Uses	4-(4-Morpholinyl)aniline is used in the preparation of central nervous system (CNS) active agents, also used in the color developing process in photographs.

4-Morpholinoaniline Preparation Products And Raw materials

Raw materials	Ethanol-->Ethyl acetate-->Methanol-->N,N-Dimethylformamide-->Potassium carbonate-->Palladium-->Dimethyl sulfoxide-->Sodium dithionite-->Morpholine-->4-Fluoronitrobenzene
Preparation Products	Momelotinib

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