Other grades of this product :
| 5-Bromoisatin Basic information |
| 5-Bromoisatin Chemical Properties |
| Melting point | 247-252 °C (lit.) | | density | 1.7498 (rough estimate) | | refractive index | 1.6120 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Soluble in N,N dimethylformamide. | | pka | 8.74±0.20(Predicted) | | form | Crystalline Powder | | color | Orange | | BRN | 383760 | | InChIKey | MBVCESWADCIXJN-UHFFFAOYSA-N | | CAS DataBase Reference | 87-48-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 37/38-41 | | Safety Statements | 26-36/39-37/39-36 | | RIDADR | 2811 | | WGK Germany | 2 | | RTECS | NL7875000 | | Hazard Note | Irritant | | HS Code | 29337900 |
| 5-Bromoisatin Usage And Synthesis |
| Chemical Properties | Orange crystalline powder | | Uses | Indole derivative | | Uses | 5-Bromoisatin is used in the synthesis of N-derivatives of 5-bromoisatin, N-substituted pyrroles, linear polyaryleneoxindoles, 5-bromodioxindole, cinchoninic acid derivatives, 3-hydroxyoxindole, S-benzyldithiocarbazate Schiff Bases, 5-bromooxindole and Morita-Baylis-Hillman adducts of isatin derivatives. It is an indole derivative. | | Synthesis Reference(s) | Tetrahedron Letters, 25, p. 3099, 1984 DOI: 10.1016/0040-4039(84)80017-9 | | General Description | 5-Bromoisatin is a 5-haloisatin. One of the methods reported for its synthesis is by reacting N-halosaccharins with isatin in the presence of SiO2. Its inotropic activity has been studied on rhythmically stimulated papillary muscles of guinea pigs. It is reported to exhibit analgesic and sedative properties at a dose of 0.2g/kg in mice. | | Purification Methods | 5-Bromoisatin forms red prisms or needles from EtOH. The N-acetate crystallises as yellow prisms from *C6H6, m 170-172o, and the N-methyl derivative forms orange-red needles from MeOH, m 172-173o. [Heller Chem Ber 53 1545 1920, Buu-Hoi Recl Trav Chim, Pays-Bas 73 197 1954, Baker etal. Tetrahedron Lett 215 1978, Beilstein 21 H 453, 21 III/IV 5009.] |
| 5-Bromoisatin Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye