2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside

2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
  • CAS No.:82373-94-2
Other grades of this product :
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Basic information
Product Name:2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside
Synonyms:2,4-Dihydroxy-6-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenyl β-D-Glucopyranoside;EH-201;Tetrahydroxystilbene glucoside;THSG;CHEMBL460860;Astragalus polyphenols;2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranosid;2,3,4,5-Tetrahydroxystilbene 2-glucoside
CAS:82373-94-2
MF:C20H22O9
MW:406.39
EINECS:683-231-5
Product Categories:chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File:82373-94-2.mol
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Chemical Properties
Boiling point 715.0±60.0 °C(Predicted)
density 1.593±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: soluble5mg/mL, clear (warmed)
form powder
pka8.78±0.40(Predicted)
color white to brown
CAS DataBase Reference82373-94-2
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 26
WGK Germany 3
HS Code 29389090
MSDS Information
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Usage And Synthesis
Uses2,3,4'',5-Tetrahydroxystilbene 2-O-Glucoside is a scavenging agent, that attenuates free radicals and upregulate antioxidant?/detoxifying enzymes to protect against oxidative damage. It also protects UB/OC-2 cells from H2O2-induced autophagy and apoptosis in vitro.
General Description2,3,5,4′ -Tetrahydroxystilbene-2-O-beta-glucoside (THSG) is a Polygoni Multiflori based polyphenol.
Biochem/physiol Actions2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside induces the expression and enhances the activity of EPO. The compound stimulates mitochondrial biogenesis, and expression of hemoglobin in non-hematopoietic cells. 2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside has demonstrated protective effects in cardiovascular disease and ischemia models.
Physiological effectsStilbene glycosides have the functions of brain protection, free radical scavenging, blood lipid lowering, liver protection, anti-tumor, vasodilation, and inhibition of atherosclerosis.
2,3,5,4'-Tetrahydroxy stilbene-2-Ο-β-D-glucoside Preparation Products And Raw materials

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